Plumeria acutifolia Poiret (Apocynaceae) is grown as an ornamental plant in India, Indonesia, Philippines and South Africa. Various species of this plant are used as medicine to cure many diseases and also as antipsychotic, diuretic, or antitumour agent. Some iridoids and triterpenoids obtained from this plant are reported to have algicidal, antibacterial and cytotoxic activity. Some species of Plumeria are also used for the cure of rheumatism, diarrhoea, blennorhea, venereal disease and leprosy. This study investigates the taxol production by Colletotrichum gloeosporioides, an endophytic fungus of Plumeria acutifolia. The presence of Taxol was confirmed through TLC, UV and IR spectroscopic methods. The amount of taxol was quantified through HPLC analysis. This is the first report that a coelomyceteous fungus producing taxol from this plant.
Keywords
Taxol, Plumeria acutifolia/I>, Colletotrichum gloeosporioides, Endophytic Fungi, Coelomycetes
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