Indian Journal of Science and Technology

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Growth Studies of Colletotrichum gloeosporioides (Penz.) Sacc. - a Taxol Producing Endophytic Fungus from Plumeria acutifolia


Affiliations
1 Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai – 600 025, India
 

Plumeria acutifolia Poiret (Apocynaceae) is grown as an ornamental plant in India, Indonesia, Philippines and South Africa. Various species of this plant are used as medicine to cure many diseases and also as antipsychotic, diuretic, or antitumour agent. Some iridoids and triterpenoids obtained from this plant are reported to have algicidal, antibacterial and cytotoxic activity. Some species of Plumeria are also used for the cure of rheumatism, diarrhoea, blennorhea, venereal disease and leprosy. This study investigates the taxol production by Colletotrichum gloeosporioides, an endophytic fungus of Plumeria acutifolia. The presence of Taxol was confirmed through TLC, UV and IR spectroscopic methods. The amount of taxol was quantified through HPLC analysis. This is the first report that a coelomyceteous fungus producing taxol from this plant.

Keywords

Taxol, Plumeria acutifolia/I>, Colletotrichum gloeosporioides, Endophytic Fungi, Coelomycetes
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  • Growth Studies of Colletotrichum gloeosporioides (Penz.) Sacc. - a Taxol Producing Endophytic Fungus from Plumeria acutifolia

Abstract Views: 606  |  PDF Views: 129

Authors

K. Nithya
Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai – 600 025, India
J. Muthumary
Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai – 600 025, India

Abstract


Plumeria acutifolia Poiret (Apocynaceae) is grown as an ornamental plant in India, Indonesia, Philippines and South Africa. Various species of this plant are used as medicine to cure many diseases and also as antipsychotic, diuretic, or antitumour agent. Some iridoids and triterpenoids obtained from this plant are reported to have algicidal, antibacterial and cytotoxic activity. Some species of Plumeria are also used for the cure of rheumatism, diarrhoea, blennorhea, venereal disease and leprosy. This study investigates the taxol production by Colletotrichum gloeosporioides, an endophytic fungus of Plumeria acutifolia. The presence of Taxol was confirmed through TLC, UV and IR spectroscopic methods. The amount of taxol was quantified through HPLC analysis. This is the first report that a coelomyceteous fungus producing taxol from this plant.

Keywords


Taxol, Plumeria acutifolia/I>, Colletotrichum gloeosporioides, Endophytic Fungi, Coelomycetes

References





DOI: https://doi.org/10.17485/ijst%2F2009%2Fv2i11%2F29528