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Comparative Study of Various Mycotoxins against few Bacterial Test Organisms


Affiliations
1 Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
 

The present investigation is an attempt to isolate various fungal sources producing mycotoxins from air and soil. Mycotoxins produced by various fungal strains are aflatoxin, gliotoxin, Penicillin, Patulin, Terrecyclic acid, Deoxynivalenol, Malformin, Fumonisin and Trichorzin. The antibacterial potential of the mycotoxins was tested against various test organisms and it was found that the aflatoxin is effective against Micrococcus luteus (MTCC No. 1538) and Pseudomonas sp. (MTCC No. 7021), in case of Gliotoxin it was observed that it has a very good antibacterial property against E. coli (MTCC No. 40), penicillin was found equally good for Micrococcus luteus (MTCC No. 1538) E. coli (MTCC No. 40). Antimicrobial activity of Patulin was observed highest against Micrococcus luteus (MTCC No. 1538), Proteus sp. (MTCC No. 426) was found to be more sensitive to Terrecyclic acid, Micrococcus sp. (MTCC No. 7527) was found most sensitive against Deoxynivalenol generating zone of inhibition 32.66 mm in case of crude and 47.66 mm in case of purified extract and Malformin was found highly effective against Proteus sp. (MTCC No. 426). The Fumonisin and Trichorzin were found as a candidate mycotoxin against Bacillus megaterium (MTCC No. 2412), Micrococcus sp. (MTCC No. 7527), Pseudomonas aeruginosa (MTCC No. 424) respectively.

Keywords

Mycotoxins, Zone of Inhibition, Antibacterial Activity.
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  • Comparative Study of Various Mycotoxins against few Bacterial Test Organisms

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Authors

Bisht Satpal Singh
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
B. Praveen
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
Panda Amrita
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
Behera Santosh
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
Panda Koustava Kumar
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
Rojita Mishra
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India
Patro Subhra Kanta
Department of Biotechnology, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India

Abstract


The present investigation is an attempt to isolate various fungal sources producing mycotoxins from air and soil. Mycotoxins produced by various fungal strains are aflatoxin, gliotoxin, Penicillin, Patulin, Terrecyclic acid, Deoxynivalenol, Malformin, Fumonisin and Trichorzin. The antibacterial potential of the mycotoxins was tested against various test organisms and it was found that the aflatoxin is effective against Micrococcus luteus (MTCC No. 1538) and Pseudomonas sp. (MTCC No. 7021), in case of Gliotoxin it was observed that it has a very good antibacterial property against E. coli (MTCC No. 40), penicillin was found equally good for Micrococcus luteus (MTCC No. 1538) E. coli (MTCC No. 40). Antimicrobial activity of Patulin was observed highest against Micrococcus luteus (MTCC No. 1538), Proteus sp. (MTCC No. 426) was found to be more sensitive to Terrecyclic acid, Micrococcus sp. (MTCC No. 7527) was found most sensitive against Deoxynivalenol generating zone of inhibition 32.66 mm in case of crude and 47.66 mm in case of purified extract and Malformin was found highly effective against Proteus sp. (MTCC No. 426). The Fumonisin and Trichorzin were found as a candidate mycotoxin against Bacillus megaterium (MTCC No. 2412), Micrococcus sp. (MTCC No. 7527), Pseudomonas aeruginosa (MTCC No. 424) respectively.

Keywords


Mycotoxins, Zone of Inhibition, Antibacterial Activity.