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Pharmacognostic Evaluation and Standardization of the leaves of Punica granatum


Affiliations
1 Department of Pharmacy, Pranveer Singh Institute of Technology (PSIT), Kanpur, India
     

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Background: As the allopathic medication system is being widely followed but the reported side effects have posed an important cause of concern hence researches are being conducted on the use of herbal medications which have given us fruitful results and complications are hardly reported. In the complete system of the medicinal loop, herbs have prominent and respective place Punica granatum leaves reveals punica granatum as a valuable medicinal plant with numerous medicinal properties. Objective: The objective of the present study is to evaluate the physicochemical and phytochemical activities of Punica granatum leaves so that its beneficial effect could be used in the treatment of diabetes. Method: The leaf powder was extracted using solvent namely ethanol, standardization is done using standard methods. The macroscopic and microscopic characters of leaves were performed in the laboratory of PSIT. Result and Conclusion: The study could be useful in diagnosis for the identification and preparation of a monograph of the plant. The Pharmacognostic evaluation of the plant was performed and diverse parameters were taken into consideration. Hence a detailed report is presented on the powder of dried leaves of Punica granatum. The macroscopical studies indicated presence of simple leaf length 2-4 cm and opposite arrangement. Physicochemical Parameters such as loss on drying and pH observed as 17.04% and 4 respectively. Chemical constituent present in it such as alkaloids, carbohydrate, reducing sugar, flavonoids and phenols. Considering all these facts we can say that ethanolic extract of Punica granatum leaves contains more constituents it can be considered beneficial for further investigation. A typical research and developmental work needs to be carried out for its better therapeutic and commercial utilization.

Keywords

Punica granatum, Diabetes, Standardization, Physicochemical, Phytochemical.
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  • Wal P, Wal A, Gupta S, Sharma G, Rai AK. Pharmacovigilance of herbal products in India. Journal of Young Pharmacists 2014; 3: 256-258.
  • Mehta D, Mehta M. Punica grantum L. (Punicaceae): lifeline for modern pharmaceutical research. Journal of Ethnopharmacology 2012; 3: 185-199.
  • Bapodara M, Nagani K, Sumitra Chanda. Pharmacogenetic and Physicochemical study of Punica granatum L. leaf Pharmacognosy Journal. 2011; 1: 29-32.
  • Bhowmik D, Gopinath H, Kumar P B, Duraivel S. Medicinal Uses of Punica granatum and Its Health Benefits. Journal of Pharmacognosy and Photochemistry. 2013; 28 -35.
  • Rahimia H.R, Arastoob M and Ostada S.N. A Comprehensive Review of Punica grantum (Pomegranate) Properties in Toxicological, Pharmacological, Cellular and Molecular Biology Researches. Iranian Journal of Pharmaceutical Research (2012), 11 (2): 385-400.
  • Saroj J.K, Ravindrabau Y, Parmar ld. study of morphological variability among fifty accessions of pomegranate (Punica granatum L.). Global general of bio science and biotechnology2017; 6 (4): 617-622
  • Russo G., Pacucci C, Pacifico A, Matarrese A.M.S. The Pomegranate, Punica granatum L.: sustainability and improvement of biodiversity in Apulia, 2012 II International Symposium on the Pomegranate 91-93. Cited on Nov 22 2018.
  • Hague N., Sofi G., Ali W, Rashid M, Itrat M. A comprehensive review of phytochemical and pharmacological profile of Anar (Punica granatum Linn): A heaven’s fruit. Journal of Ayurvedic and Herbal Medicine 2015; 1(1): 22-26.
  • Khandelwal KR. Practical Pharmacognosy. Nirali Publication, India. 2008; 20-25
  • Pal R.S, Pal Y, Wal P and Wal A . Pharmacogenetic Evaluation of Roots of Benincasa hispida (Thunb.) Cogn (Cucurbitaceae). The Open Plant Science Journal, 2018; 11(3).
  • Kumari, Dora J, Kumar A and Kumar A. Pomegranate (Punica granatum)-Overview International Journal of Pharmaceutical and Chemical Sciences 2017; 1 (4):1218-1222.
  • Edwin S, Joshi SB, Jain DC. Comparative pharmacognostical studies on ischolar_main powder of Plumbago zeylanica and Plumbago rosea. Indian Journal of Natural Product 2008; 2: 27-9.
  • Gupta MK, Sharma PK, Ansari SH, Lagarkha RE. Pharmacognostical evaluation of Grewia asiatica fruits. International Journal of Plant Science 2006; 1(2): 249-51.
  • Mukherjee PK. Quality Control of Herbal Drugs: An Approach to Evaluation of Botanicals. Business Horizons Publishers, New Delhi, India. 2002.
  • Forty-sixth WHO Expert Committee on Specifications for Pharmaceutical Preparations in October 2011 for addition to the 4th Edition of the International Pharmacopoeia.
  • Mehta, A.; Barker, G. C. "The dynamics of sand". Reports on Progress in Physics.1991; 57 (4): 383. Bibcode:
  • Bower, Michael I. and P. Heinrich Stahl. 2008. "Preparation of Water-Soluble Compounds through Salt Formation." In Camille Georges Wermuth. The Practice of Medical Chemistry, pp. 747– 766. Burlington, MA: Elsevier, pg. 756.
  • Beddow, J. K. 1995. "Professor Dr. Henry H. Hausner, 1900–1995." Particle and Particle Systems Characterization 12: 213. doi:10.1002/ppsc.19950120411

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  • Pharmacognostic Evaluation and Standardization of the leaves of Punica granatum

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Authors

Pranay Wal
Department of Pharmacy, Pranveer Singh Institute of Technology (PSIT), Kanpur, India
Rashmi Saxena Pal
Department of Pharmacy, Pranveer Singh Institute of Technology (PSIT), Kanpur, India
Nikita Saraswat
Department of Pharmacy, Pranveer Singh Institute of Technology (PSIT), Kanpur, India
Rachana Yadav
Department of Pharmacy, Pranveer Singh Institute of Technology (PSIT), Kanpur, India

Abstract


Background: As the allopathic medication system is being widely followed but the reported side effects have posed an important cause of concern hence researches are being conducted on the use of herbal medications which have given us fruitful results and complications are hardly reported. In the complete system of the medicinal loop, herbs have prominent and respective place Punica granatum leaves reveals punica granatum as a valuable medicinal plant with numerous medicinal properties. Objective: The objective of the present study is to evaluate the physicochemical and phytochemical activities of Punica granatum leaves so that its beneficial effect could be used in the treatment of diabetes. Method: The leaf powder was extracted using solvent namely ethanol, standardization is done using standard methods. The macroscopic and microscopic characters of leaves were performed in the laboratory of PSIT. Result and Conclusion: The study could be useful in diagnosis for the identification and preparation of a monograph of the plant. The Pharmacognostic evaluation of the plant was performed and diverse parameters were taken into consideration. Hence a detailed report is presented on the powder of dried leaves of Punica granatum. The macroscopical studies indicated presence of simple leaf length 2-4 cm and opposite arrangement. Physicochemical Parameters such as loss on drying and pH observed as 17.04% and 4 respectively. Chemical constituent present in it such as alkaloids, carbohydrate, reducing sugar, flavonoids and phenols. Considering all these facts we can say that ethanolic extract of Punica granatum leaves contains more constituents it can be considered beneficial for further investigation. A typical research and developmental work needs to be carried out for its better therapeutic and commercial utilization.

Keywords


Punica granatum, Diabetes, Standardization, Physicochemical, Phytochemical.

References