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Important Role, Isolation and Basic Concept of Resealed Erythrocytes


Affiliations
1 GNIT College of Pharmacy, Plot No.6 C, Knowledge Park 2, Greater Noida, Uttar Pradesh, 201306, India
2 Department of Pharmaceutics, SGT College of Pharmacy, SGT University Budhera, Gurugram, Haryana 122505, India
     

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Among the most important being biocompatibility of carrier and its degradation products erythrocytes the most investigated and have found to possess greater potential in drug delivery Erythrocytes, also known as red blood cells, and have been extensively studied for their potential carrier capabilities for the delivery of drugs. The biocompatibility, non-pathogenicity, non-immunogenicity and biodegradability make them unique and useful carriers. Carrier erythrocytes are prepared by collecting blood sample from the organism of interest and separating erythrocytes from plasma. The concept of employing erythrocytes as drug or bio active carrier still needs further optimization a large amount of valuable work is needed so us to utilize the potential of erythrocyte in passive and as well as active targeting of drugs. Disease like cancer would surely find it cure. Genetic engineering aspects can be coupled to give a newer dimension to the existing cellular drug concept.

Keywords

Erythrocytes, Carrier, Blood, Plasma.
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  • Important Role, Isolation and Basic Concept of Resealed Erythrocytes

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Authors

Anil Kumar Sahdev
GNIT College of Pharmacy, Plot No.6 C, Knowledge Park 2, Greater Noida, Uttar Pradesh, 201306, India
Bhawana Sethi
Department of Pharmaceutics, SGT College of Pharmacy, SGT University Budhera, Gurugram, Haryana 122505, India

Abstract


Among the most important being biocompatibility of carrier and its degradation products erythrocytes the most investigated and have found to possess greater potential in drug delivery Erythrocytes, also known as red blood cells, and have been extensively studied for their potential carrier capabilities for the delivery of drugs. The biocompatibility, non-pathogenicity, non-immunogenicity and biodegradability make them unique and useful carriers. Carrier erythrocytes are prepared by collecting blood sample from the organism of interest and separating erythrocytes from plasma. The concept of employing erythrocytes as drug or bio active carrier still needs further optimization a large amount of valuable work is needed so us to utilize the potential of erythrocyte in passive and as well as active targeting of drugs. Disease like cancer would surely find it cure. Genetic engineering aspects can be coupled to give a newer dimension to the existing cellular drug concept.

Keywords


Erythrocytes, Carrier, Blood, Plasma.

References