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A Comparison Study of Nefopam ketamine, Tramadol ketamine and Xylazine ketamine anesthesia in Rabbit


Affiliations
1 College of Veterinary Medicine, University of Kerbala, Karbala, Iraq
2 College of Nursing, University of Misan, Misan, Iraq
     

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This study were preformed to evaluate and compare between three anesthetic regime, using injectable anesthesia (Nefopam/ketamine), (Tramadol / Ketamine) and (xylazine/ketamine) in anesthetic protocols in rabbits. Eighteen adult local breed rabbits from both sexes weighing (1.1-1.8) Kg. were divided equally into three groups they were housed indoor to accommodate the place of experiments. The following physiological parameters (heart rate, respiratory rate and rectal body temperature) were recorded before the intramuscular injection of the drugs for each group (zero time) as a self group. Group (A) were injected tramadol hydrochloride 10% 15 mg/kg B.W as premedication, after 10min. Ketamine hydrochloride 10% at a dose of 10 mg/kg, 50 mg/kg B.W., group (B) were injected Xylazine 2%10mg/kg B.W. as premedication, after 10min. the animals were injected as same in group (A). and group (C) were injected Nefopam 2% mg/kg B.W. as premedication, after 10min. the animals were injected as same in group (A) and (B). Stages of anesthesia (induction time, surgical time and recovery time) and physiologic parameters (heart rate, respiratory rate and Rectal body temperature) were evaluated. The most significant changes were reported in group (B) which useful regimen clinically for anesthetize rabbits due to long surgical time.

Keywords

Nefopam, Ketamine, Tramadol, Anaesthesia.
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  • A Comparison Study of Nefopam ketamine, Tramadol ketamine and Xylazine ketamine anesthesia in Rabbit

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Authors

Jassim M. Khalaf Albozachri
College of Veterinary Medicine, University of Kerbala, Karbala, Iraq
Hayder M. AL-Tomah
College of Veterinary Medicine, University of Kerbala, Karbala, Iraq
Osamah N. Wali
College of Nursing, University of Misan, Misan, Iraq
Yasser J. Jameel
College of Veterinary Medicine, University of Kerbala, Karbala, Iraq

Abstract


This study were preformed to evaluate and compare between three anesthetic regime, using injectable anesthesia (Nefopam/ketamine), (Tramadol / Ketamine) and (xylazine/ketamine) in anesthetic protocols in rabbits. Eighteen adult local breed rabbits from both sexes weighing (1.1-1.8) Kg. were divided equally into three groups they were housed indoor to accommodate the place of experiments. The following physiological parameters (heart rate, respiratory rate and rectal body temperature) were recorded before the intramuscular injection of the drugs for each group (zero time) as a self group. Group (A) were injected tramadol hydrochloride 10% 15 mg/kg B.W as premedication, after 10min. Ketamine hydrochloride 10% at a dose of 10 mg/kg, 50 mg/kg B.W., group (B) were injected Xylazine 2%10mg/kg B.W. as premedication, after 10min. the animals were injected as same in group (A). and group (C) were injected Nefopam 2% mg/kg B.W. as premedication, after 10min. the animals were injected as same in group (A) and (B). Stages of anesthesia (induction time, surgical time and recovery time) and physiologic parameters (heart rate, respiratory rate and Rectal body temperature) were evaluated. The most significant changes were reported in group (B) which useful regimen clinically for anesthetize rabbits due to long surgical time.

Keywords


Nefopam, Ketamine, Tramadol, Anaesthesia.

References