Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Comparative Study of Antimicrobial and Antioxidant Activity between Seeds and Leaves of Crude Drug Moringa oleifera


Affiliations
1 Manoharbhai Patel Institute of B-Pharmacy, Kudwa Gondia, India
     

   Subscribe/Renew Journal


Dietary intervention the successful strategy to protect human bodies from health problems link to oxidative stress. Currently the medicinal plants are widely utilized for various purposes as antimicrobial and antioxidant according to their components. The aim of the present study, the well cup plate method carried out to asses antimicrobial activity extract of leaves and extract of seeds. In addition, their antioxidant activity potential has been evaluated by using DPPH Radical scavenging assay and Free Radical Scavenging assay. The exhibited that leaves extract was the highest antimicrobial activity against E. coli and S. aureus. While, The minimum activity was observed in extract of seeds against E. coli and S. aureus. On the other hand antioxidant activity, DPPH Radical scavenging activity and Free Radical Scavenging activity was found to be highest in leaves extract and lowest in seeds extract. From study, it is determine that leaves extract of Moringa oliefera is antimicrobial agent and antioxidant agent to that of seeds extract.

Keywords

Moringa oleifera, Leaves and Seeds, Antimicrobial, Antioxidant, Photochemicals.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Roloff, H. Weisgerber, U. Lang, B. Stimm. Enzyklopadie der Holzgewachse, Handbuch and Atlas der Dendrology 2009,1-8.

  • Ram P. Rastogi, B.N. Mehrotra. Compendium of Indian Medicinal Plants. Central drug Research Institute, Lucknow and National Institute of Science Communication and Information Resources, New Delhi, Vol. 4,2004,484.

  • Kumar A and Pari L: Antioxidant action of Moringa oliefera Lam (drumstick) against antitubercular drugs induced lipid peroxidation in rats. Journal of Medical Food 2003;6:255-259.

  • Sreelatha S and Padma PR: Antioxidant activity and total phenolic content of Moringa oliefera leaves in two stages of maturity. Plant Foods Hum Nutr 2009; 64(4):303-11.

  • Halliwell, B. ,2008 Arch. Biochem. Biophys. 476(2), 107-112.

  • Johnson, I. T. ,2007 , Proc. Nutr. Soc. , 66 (2), 207-215.

  • Anwar F, Latif S, Ashraf M Gilani AH: Moringa oleifera: Food plant with multiple medicinal uses: phytother Res2007; 21 (1) : 17-25.

  • K. M. Nadkarni . Indian Materia Media. Bombay Popular Prakashan, 2009, volume 1,811-816.

  • Mishra Garima, Singh Pradeep, Verma Ramesh et al, Traditional uses, Phytochemistry and Pharmacological properties of Moringa oliefera plant; An overview, scholars Research Library, 2011; 3(2): 141-164.

  • Goyal Bhoomika, Agrawal Babita, Goyal Ramesh, Mehta Anita, Phytopharmacology of Moringa oliefera lam.: An overview Natural Product Radiance, 2007,6(4:347-253).

  • Bajpai M ,Pande A. , Tiwari S K and Prakash D: phenolic content and antioxidant activity of some food sci. Nutr 2005; 56(4):287-91.

  • Wiwit Denny Fitrina, Taslim Ersam, et al: Antioxidant Activity of Moringa oliefera extracts 2016,16(3),297-301.


Abstract Views: 171

PDF Views: 0




  • Comparative Study of Antimicrobial and Antioxidant Activity between Seeds and Leaves of Crude Drug Moringa oleifera

Abstract Views: 171  |  PDF Views: 0

Authors

Nitin H. Indurwade
Manoharbhai Patel Institute of B-Pharmacy, Kudwa Gondia, India
Sunil B. Chaudhari
Manoharbhai Patel Institute of B-Pharmacy, Kudwa Gondia, India
Rina G. Maskare
Manoharbhai Patel Institute of B-Pharmacy, Kudwa Gondia, India
Juhi U. Bandre
Manoharbhai Patel Institute of B-Pharmacy, Kudwa Gondia, India
Nikhil Bhivgade
Manoharbhai Patel Institute of B-Pharmacy, Kudwa Gondia, India

Abstract


Dietary intervention the successful strategy to protect human bodies from health problems link to oxidative stress. Currently the medicinal plants are widely utilized for various purposes as antimicrobial and antioxidant according to their components. The aim of the present study, the well cup plate method carried out to asses antimicrobial activity extract of leaves and extract of seeds. In addition, their antioxidant activity potential has been evaluated by using DPPH Radical scavenging assay and Free Radical Scavenging assay. The exhibited that leaves extract was the highest antimicrobial activity against E. coli and S. aureus. While, The minimum activity was observed in extract of seeds against E. coli and S. aureus. On the other hand antioxidant activity, DPPH Radical scavenging activity and Free Radical Scavenging activity was found to be highest in leaves extract and lowest in seeds extract. From study, it is determine that leaves extract of Moringa oliefera is antimicrobial agent and antioxidant agent to that of seeds extract.

Keywords


Moringa oleifera, Leaves and Seeds, Antimicrobial, Antioxidant, Photochemicals.

References