Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Phytochemical Screening and In-Vitro Antioxidant activity of Senna occidentalis


Affiliations
1 Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education and Research, Narsapur Medak, India
     

   Subscribe/Renew Journal


The aim of this article is to evaluate antioxidant activity of leaf extract of Senna occidentalis by using in vitro assay. Extraction was carried out with ethanol extract by using Soxhlet apparatus. The in-vitro antioxidant activity ethanol extract has been investigated by 1, 1-diphenyl,2-picryl–hydrazyl free radical (DPPH) method. The ethanol extract exhibited maximum antioxidant activity. The results have been compared with the standard ascorbic acid. The Ethanolic leaf extract of Senna occidentalis shows IC50 value at 7 μg/ml.

Keywords

Antioxidant Activity, DPPH, Free Radicals, Ethanolic Extract, Ascorbic Acid.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Duberstein W, Reglitzky A, Schütze A, Reders K (2007). "Automotive Fuels ".Ullmann's Encyclopedia of Industrial Chemistry. doi10.1002/14356007.a16_719.pub2ISBN 978-3-527- 30673-2

  • Hall C. Sources of natural antioxidants: oilseeds, nuts, cereals, legumes, animal products and microbial sources. In: Pokorny J, Yanishlieva N, Gordon M, editors. Antioxidants in food: practical applications,

  • Cambridge England: Woodhead Publishing Limited, 2001, 159-209.McCord, J.M. The evolution of free radicals and oxidative stress.Am. J. Med. 2000, 108, 652–659.

  • Suhaj M. Spice antioxidants isolation and their antiradical activity: a review. Journal of Food Composition and Analysis 2006; 19, 531–537.

  • Journal of Ethno pharmacology Volume 71, Issues 1–2, July 2000, Pages 23-43

  • Blomhoff R, Dietary antioxidants and cardiovascular disease. Curr.Opin. Lip idol. 16, 2005; 47-54.

  • Bourgeois CF, Antioxidant vitamins and health: cardiovascular disease, cancer, cataracts, and aging, HNB Publishing, New York, USA, 2003.

  • Wu YY, Li W, Xu Y, Jin EH, Tu YY. Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses. J Zhejiang UnivSci B. 2011;12:744–751. [PMC free article] [PubMed]

  • Prashant KR, Dolly J, Singh KR, Gupta KR, Watal G. Glycemic properties of Trichosanthesdioica leaves. Pharm Biol. 2008;46 (12):894–899.

  • Jigna P, Sumitra C. In-vitro antimicrobial activities of extracts of LaunaeaprocumbensRoxb. (Labiateae), Vitisvinifera L. (Vitaceae) and Cyperusrotundus L. (Cyperaceae) Afr J Biomed Res. 2006;9:89–93.

  • Chandaka Madhu L, Harish K, Narsimha Reddy S, SagarD, Soumya G,PavanKumar.Antiurolithic activity of aqueous extract on ischolar_mains and seeds of Plectranthustomentora on ethylene glycol induced kidney stones in male albino rats. Asian J Res Pharm Sci, 2012; 2(4):129-133.

  • K. Purushotham, I. Srikanth, P. Nandeeshwar, Dr.K. Ramanjaneyulu, J. Himabindhu. In Vitro Anthelmintic Activity of Sennaoccidentalis .IJSRM, December 2017 Vol.:8

  • Shen Q, Zhang B, Xu R, Wang Y, Ding X, Li P. Antioxidant activity in vitro of selenium-contained protein from the se-enriched. Bifodobacteriumanimalis 01.Anaerobe, 2010; 16: 380-386.


Abstract Views: 170

PDF Views: 0




  • Phytochemical Screening and In-Vitro Antioxidant activity of Senna occidentalis

Abstract Views: 170  |  PDF Views: 0

Authors

K. Purushotham
Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education and Research, Narsapur Medak, India
P. Nandeeshwar
Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education and Research, Narsapur Medak, India
I. Srikanth
Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education and Research, Narsapur Medak, India
K. Ramanjaneyulu
Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education and Research, Narsapur Medak, India
J. Himabindhu
Department of Pharmacognosy, Vishnu Institute of Pharmaceutical Education and Research, Narsapur Medak, India

Abstract


The aim of this article is to evaluate antioxidant activity of leaf extract of Senna occidentalis by using in vitro assay. Extraction was carried out with ethanol extract by using Soxhlet apparatus. The in-vitro antioxidant activity ethanol extract has been investigated by 1, 1-diphenyl,2-picryl–hydrazyl free radical (DPPH) method. The ethanol extract exhibited maximum antioxidant activity. The results have been compared with the standard ascorbic acid. The Ethanolic leaf extract of Senna occidentalis shows IC50 value at 7 μg/ml.

Keywords


Antioxidant Activity, DPPH, Free Radicals, Ethanolic Extract, Ascorbic Acid.

References