Research Journal of Pharmacy and Technology

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The Relationship between Metabolic Factors and Quality of Life Aspects in Type 2 Diabetes Patients


Affiliations
1 Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
2 Nutrition Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
3 Diabetes Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
4 Department of Biostatistics and Epidemiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
     

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Background and Objective: Quality of life (QoL) significantly influences the therapeutic outcomes in diabetic patients. The present study aimed to investigate the impacts of different aspects of QoL of patients with metabolic factors. Methods: This cross-sectional descriptive study recruited 263 patients (mean age 51.79 years) with type 2 diabetes (T2D). Data were collected using demographic information form, the Persian version of the 36-item health-related QoL and Audit of Diabetes-Dependent Quality of Life (ADDQoL) questionnaires. Clinical and laboratory tests including total cholesterol, HDL-C and LDL-C were also performed. Statistical analysis was performed with statistical package SPSS version 22.0. Results: The mean total score of Diabetes Quality of Life (DQoL) was 53.54 ± 20.85 based on SF-36. The overall score of QoL showed a negative significant correlation with the levels of FBS, HbA1C and triglycerides (P<0.05). A statistically significant negative correlation was observed between physical health and total cholesterol levels, between mental health and QoL with FBS (P=0.000), HbA1c (P=0.001) and total cholesterol (P=0.024); however, no significant correlation was observed with other parameters. Conclusion: Improvements in metabolic control have a significant effect on the Quality of Life among Adult T2D patients.

Keywords

Audit of Diabetes-Dependent Quality of Life, Quality of Life, Type 2 Diabetic, Fasting Glucose, Lipid Profile, Glycosylated Hemoglobin.
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  • The Relationship between Metabolic Factors and Quality of Life Aspects in Type 2 Diabetes Patients

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Authors

Fatemeh Haidari
Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
Esmat Mansoori
Nutrition Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
Mehrnoosh Zakerkish
Diabetes Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran, Islamic Republic of
Mohammadhossein Haghighizadeh
Department of Biostatistics and Epidemiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic of

Abstract


Background and Objective: Quality of life (QoL) significantly influences the therapeutic outcomes in diabetic patients. The present study aimed to investigate the impacts of different aspects of QoL of patients with metabolic factors. Methods: This cross-sectional descriptive study recruited 263 patients (mean age 51.79 years) with type 2 diabetes (T2D). Data were collected using demographic information form, the Persian version of the 36-item health-related QoL and Audit of Diabetes-Dependent Quality of Life (ADDQoL) questionnaires. Clinical and laboratory tests including total cholesterol, HDL-C and LDL-C were also performed. Statistical analysis was performed with statistical package SPSS version 22.0. Results: The mean total score of Diabetes Quality of Life (DQoL) was 53.54 ± 20.85 based on SF-36. The overall score of QoL showed a negative significant correlation with the levels of FBS, HbA1C and triglycerides (P<0.05). A statistically significant negative correlation was observed between physical health and total cholesterol levels, between mental health and QoL with FBS (P=0.000), HbA1c (P=0.001) and total cholesterol (P=0.024); however, no significant correlation was observed with other parameters. Conclusion: Improvements in metabolic control have a significant effect on the Quality of Life among Adult T2D patients.

Keywords


Audit of Diabetes-Dependent Quality of Life, Quality of Life, Type 2 Diabetic, Fasting Glucose, Lipid Profile, Glycosylated Hemoglobin.