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Embryonal Rhabdomyosarcoma of Oral Cavity with Extensive Osteolysis of the Mandible – A Rare Case Report


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1 Department of Oral Medicine and Radiology, Tamil Nadu Govt. Dental College and Hospital, Chennai 600003, Tamil Nadu, India
     

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Rhabdomyosarcoma is a malignant tumor of skeletal muscle. It is the most common soft tissue sarcoma in children and adolescents. It rarely occurs in oral cavity and accounts for 0.04% of all head and neck malignancies. The incidence is 4.5 per 1 million children and 50% of cases are seen in the first decade of life. In this paper, we report a rare case of oral rhabdomyosarcoma in a 3 year old boy with involvement of buccal mucosa and extensive destruction of the mandible.

Keywords

Sarcoma, Malignant Tumor, Rhabdomyosarcoma.
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  • Wang C. Childhood rhabdomyosarcoma: recent advances and prospective views. J Dent Res. 2012;91:341–350.
  • Al-Khateeb T, Bataineh AB. Rhabdomyosarcoma of the oral and maxillofacial region in Jordanians: a retrospective analysis. Oral surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93:580–585.
  • Parham DM. Pathological classification of rhabdomyosarcomas and correlations with molecular studies. Mod Pathol. 2001;14(5):506–514.
  • Dagher R. Helman L- rhabdomyosarcoma: an overview. The Oncologist. 1999;4:34–44.
  • Scrable HJ, Witte DP, Lampkin BC, et al. Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping. Nature. 1987;329:645–647.
  • Scrable H, Witte D, Shimada H, et al. Molecular differential pathology of rhabdomyosarcoma. Genes Chromosomes Cancer. 1989;1:23–35.
  • El Badry OM, Minniti C, Kohn EC, et al. Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ. 1990;1:325–331.
  • Sekhar MS, Desai S, Kumar GS. Alveolar rhabdomyosarcoma involving the jaws: a case report. J Oral Maxillofac Surg. 2000;58:1062–1065.
  • Geeta S, Shadab M, Nidhi V, Somdipto D. Intraoral Pleomorphic Rhabdomyosarcoma: a case report. Oral Maxillofacial Pathol J. 2013;4(2):403–407.
  • Franca CM, Caran EM, Alves MT, Barreto AD, Lopes NN. Rhabdomyosarcoma of the oral tissues – two new cases and literature and review. Med Oral Patol Oral Cir Bucal. 2006;11:136–140.
  • Wexler L, Helman L. Rhabdomyosarcoma and the undifferentiated sarcomas. In: Pizzo P, Poplack D, eds. In: Principles and Practice of Pediatric Oncology 3rd edition Philadelphia: Lippincott-Raven, Miloglu; 1997:799–829.
  • Askew C, Fleming PS, Flood TR. Successful multimodal management of rhabdomyosarcoma and dentofacial sequelae of treatment. Oral Oncol Extra. 2006;42: 52–55.
  • Nayar R, Prudhomme F, Parise Jr et al. Rhabdomyosarcoma of the head and neck in adults. 1993;103:1362–1366.
  • Miloglu O, Altas SS, Buyukkurt MC, Erdemci B, Altun O. Rhabdomyosarcoma of the oral cavity: a case report. Eur J Dent. 2011;5:340–343.
  • Kaur P, Kaur A, Suri AK, Malik H. J Clin Diagn Res. 2016;10 (8):17–18.
  • Rajwanshi A, Srinivas R, Upasana G. Malignant small round cell tumours. J Cytol. 2009;26(1):1–10.
  • Hall JH, Yohe SL. Application of immunohistochemistry to soft tissue neoplasms. Arch Pathol Lab Med. 2008;132(3): 476–489.
  • Sbiity S, Abella A, Arcand P, Quintal MC, Saliba I. Temporal bone rhabdomyosarcoma in children. Int J Pediatr Otohinolaryngol. 2007;71(5):807–814. May.
  • Scully C, Sonis S, Diz PD. Oral mucositis. Oral Dis. 2006;12 (3):229–241.
  • Suresh D, Manjula M, Kumuda P, Aruna P. Embryonal rhabdomyosarcoma of the oral cavity – a case report. J Res Adv Dent. 2013;2(2):78–81.

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  • Embryonal Rhabdomyosarcoma of Oral Cavity with Extensive Osteolysis of the Mandible – A Rare Case Report

Abstract Views: 150  |  PDF Views: 0

Authors

Vidya Jayaram
Department of Oral Medicine and Radiology, Tamil Nadu Govt. Dental College and Hospital, Chennai 600003, Tamil Nadu, India
S. Jayachandran
Department of Oral Medicine and Radiology, Tamil Nadu Govt. Dental College and Hospital, Chennai 600003, Tamil Nadu, India
Y. Hemavathy Bhaskar
Department of Oral Medicine and Radiology, Tamil Nadu Govt. Dental College and Hospital, Chennai 600003, Tamil Nadu, India

Abstract


Rhabdomyosarcoma is a malignant tumor of skeletal muscle. It is the most common soft tissue sarcoma in children and adolescents. It rarely occurs in oral cavity and accounts for 0.04% of all head and neck malignancies. The incidence is 4.5 per 1 million children and 50% of cases are seen in the first decade of life. In this paper, we report a rare case of oral rhabdomyosarcoma in a 3 year old boy with involvement of buccal mucosa and extensive destruction of the mandible.

Keywords


Sarcoma, Malignant Tumor, Rhabdomyosarcoma.

References