Journal of Natural Remedies

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Objective: To investigate the effects of Cassia singueana on the central nervous system in mice. Materials and methods: The effects of methanol extract of Cassia singueana on motor coordination, spontaneous motor activity, pentobarbital sleeping time and exploratory behaviour were evaluated in mice. Results: The extract failed to exhibit activity on motor coordination test, but significantly reduced spontaneous motor activity and exploratory behaviour, and prolonged barbital hypnosis. Conclusion: The extract contains potent neuropharmacological principle with sedative effect.

Keywords

Cassia singueana, Sedation
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