Journal of Natural Remedies

The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off


Objective: To evaluate the different extracts of Psidium guajava bark for its antidiarrhoeal potential against several experimental models of diarrhoea in rats. Materials and methods: Antidiarrhoeal activity of methanolic and aqueous extracts of Psidium guajava bark was studied at dose of 50 mg/kg and 100 mg/kg body weight against gastrointestinal motility, castor oil-induced diarrhoea and prostaglandin E2-inducead enteropooling (PGE2) in rats. Results: The methanolic and aqueous extracts of P. guajava bark showed significant antidiarrhoeal activity in a dose dependent manner against all the experimental diarrhoea models. The potent antidiarrhoeal activity may be attributed to the presence of tannin and quercetin. Conclusion: The results indicated that both the extracts of P. guajava bark at dose of 100 mg/kg were found to be more potent than the reference standard drugs, loperamid and atropine.

Keywords

, Bark
Font Size

User

Notifications
JOURNAL COVERS