Journal of Natural Remedies

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Ayurvedic Management of Polypoidal Choroidal Vasculopathy (PCV) -A Case Report


Affiliations
1 Department of Shalakya Tantra, Amrita School of Ayurveda, Kollam – 690546, Kerala, India
 

Polypoidal Choroidal Vasculopathy (PCV), a subtype of neovascular Age-related Macular Degenerationn (AMD) is a disease characterized by persistent, recurrent serous leakage and hemorrhage in the macular area, mostly seen in the elderly population. While contemporary science offers anti Vasculo Endothelial Growth Factor (VEG-F) monotherapy and combination with Photodynamic Therapy (PDT), the outcomes of these remain doubtful. Repeated anti-VEG-F injections not only cause a financial and mental burden on the patients with no or very little visual outcome. Chronicity paves the way to complete loss of vision due to exudative retinal detachment. Symptoms like Raktavatdristi (to visualize things as if through a column of blood), Pashyatiaasyamanaasikam (unable to recognize the faces of people around) and aaviladarshanam (blurred vision) were suggestive of Raktaja Timira (an eye disease caused by Raktadosa) associated with Kaphadushti), according to Ayurveda.

A 77-year-old male patient diagnosed with PCV sought Ayurvedic treatment after being advised to undergo anti-VEG-F therapy for the 3rd time in a row. His treatment comprised internal medicines consisting of Mahatiktakakashaya, Guduchyadikashaya, Chandraprabhavati and Avipathichurna; external treatments like Pratimarshanasya with Anu tailam and Gandusha with Triphalakashaya; Kriyakalpa (eye treatments) like Seka, Vidalaka, Aschotana and Anjana karma.

At the end of 3 months of Ayurvedic treatment, his visual acuity in the right eye improved to 6/6, Optical Coherence Tomography (OCT) affirmed complete normalcy of the macula and Fundus examination confirmed the absence of neovascularization. Ayurvedic treatment is effective in reversing the process of neovascularization, thereby bringing about the marked visual outcome in PCV. Such patients should be encouraged to adopt Ayurvedic treatment instead of expensive and invasive treatment procedures like intra-vitreal injections even when the absolute effects of these remain doubtful.


Keywords

Anjana Karma, Neovascular Age-related Macular Degeneration, Posterior Vitreous Detachment, Raktajatimira, Seka .
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  • Cheung CMG, Lai TYY, Ruamviboonsuk P, Chen SJ, Chen Y, Freund KB, et al. Polypoidal Choroidal Vasculopathy: Definition, Pathogenesis, Diagnosis, and Management. Ophthalmology. 2018. DOI: https://doi.org/10.1016/j.ophtha.2017.11.019

  • Teo KYC, Gillies M, Fraser-Bell S. The use of vascular endothelial growth factor inhibitors and complementary treatment options in polypoidal choroidal vasculopathy: A subtype of neovascular age-related macular degeneration. International Journal of Molecular Sciences. 2018. DOI: https://doi.org/10.3390/ijms19092611

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  • Ayurvedic Management of Polypoidal Choroidal Vasculopathy (PCV) -A Case Report

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Authors

K. Shanti
Department of Shalakya Tantra, Amrita School of Ayurveda, Kollam – 690546, Kerala, India

Abstract


Polypoidal Choroidal Vasculopathy (PCV), a subtype of neovascular Age-related Macular Degenerationn (AMD) is a disease characterized by persistent, recurrent serous leakage and hemorrhage in the macular area, mostly seen in the elderly population. While contemporary science offers anti Vasculo Endothelial Growth Factor (VEG-F) monotherapy and combination with Photodynamic Therapy (PDT), the outcomes of these remain doubtful. Repeated anti-VEG-F injections not only cause a financial and mental burden on the patients with no or very little visual outcome. Chronicity paves the way to complete loss of vision due to exudative retinal detachment. Symptoms like Raktavatdristi (to visualize things as if through a column of blood), Pashyatiaasyamanaasikam (unable to recognize the faces of people around) and aaviladarshanam (blurred vision) were suggestive of Raktaja Timira (an eye disease caused by Raktadosa) associated with Kaphadushti), according to Ayurveda.

A 77-year-old male patient diagnosed with PCV sought Ayurvedic treatment after being advised to undergo anti-VEG-F therapy for the 3rd time in a row. His treatment comprised internal medicines consisting of Mahatiktakakashaya, Guduchyadikashaya, Chandraprabhavati and Avipathichurna; external treatments like Pratimarshanasya with Anu tailam and Gandusha with Triphalakashaya; Kriyakalpa (eye treatments) like Seka, Vidalaka, Aschotana and Anjana karma.

At the end of 3 months of Ayurvedic treatment, his visual acuity in the right eye improved to 6/6, Optical Coherence Tomography (OCT) affirmed complete normalcy of the macula and Fundus examination confirmed the absence of neovascularization. Ayurvedic treatment is effective in reversing the process of neovascularization, thereby bringing about the marked visual outcome in PCV. Such patients should be encouraged to adopt Ayurvedic treatment instead of expensive and invasive treatment procedures like intra-vitreal injections even when the absolute effects of these remain doubtful.


Keywords


Anjana Karma, Neovascular Age-related Macular Degeneration, Posterior Vitreous Detachment, Raktajatimira, Seka .

References





DOI: https://doi.org/10.18311/jnr%2F2023%2F30620