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A Review on Phytoconstituents and Metal Complexes for the Treatment of Tuberculosis


Affiliations
1 Dr. APJ Abdul Kalam Research Laboratory, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur – 603203, Tamil Nadu, India
 

Tuberculosis (TB) is an infectious lung disease. Tiny droplets discharged into the air during cough and sneezes by an individual can transmit the bacteria that cause tuberculosis from one person to another. More than one million people die each year as a result of the communicable disease tuberculosis. Anti-TB allopathic drugs have been administered to treat the disease’s symptoms; however, they can produce negative side effects such as hepatitis, hypersensitivity reactions, nausea, vomiting, etc. As a result of the toxicity and side effects of allopathic medicines, the use of herbal medicine is growing in popularity. Since ancient times, medicinal plants have been used to treat illnesses. Alkaloids, coumarins, flavonoids, polyphenols, terpenoids, quinines, and other secondary metabolites that have antibacterial activity are produced by plants and may be helpful in the treatment of tuberculosis. This review aims to explore the possible uses of medicinal herbs and metal complexes with antitubercular capabilities.

Keywords

Iron Complex, Metal Complex, Terpenes, Tuberculosis.
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  • A Review on Phytoconstituents and Metal Complexes for the Treatment of Tuberculosis

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Authors

Sk. Zakki Uddin
Dr. APJ Abdul Kalam Research Laboratory, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur – 603203, Tamil Nadu, India
Nirupama Panda
Dr. APJ Abdul Kalam Research Laboratory, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur – 603203, Tamil Nadu, India
G. V. Anjana
Dr. APJ Abdul Kalam Research Laboratory, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur – 603203, Tamil Nadu, India
M. K. Kathiravan
Dr. APJ Abdul Kalam Research Laboratory, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur – 603203, Tamil Nadu, India

Abstract


Tuberculosis (TB) is an infectious lung disease. Tiny droplets discharged into the air during cough and sneezes by an individual can transmit the bacteria that cause tuberculosis from one person to another. More than one million people die each year as a result of the communicable disease tuberculosis. Anti-TB allopathic drugs have been administered to treat the disease’s symptoms; however, they can produce negative side effects such as hepatitis, hypersensitivity reactions, nausea, vomiting, etc. As a result of the toxicity and side effects of allopathic medicines, the use of herbal medicine is growing in popularity. Since ancient times, medicinal plants have been used to treat illnesses. Alkaloids, coumarins, flavonoids, polyphenols, terpenoids, quinines, and other secondary metabolites that have antibacterial activity are produced by plants and may be helpful in the treatment of tuberculosis. This review aims to explore the possible uses of medicinal herbs and metal complexes with antitubercular capabilities.

Keywords


Iron Complex, Metal Complex, Terpenes, Tuberculosis.

References





DOI: https://doi.org/10.18311/jnr%2F2023%2F32121