International Journal of Physiology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Study of Evoked Potentials in Central Demyelinating Disorders Versus Nondemyelinating Disorders


Affiliations
1 Associate Professor, Department of Physiology, Sree Mookambika Medical College & Research Institute, Kulasekharam, Kanyakumari
2 Additional Professor, Department f Physiology
3 Professor, Department of Neurology, JIPMER, Pondicherry
     

   Subscribe/Renew Journal


We studied brainstem auditory, somatosensory and visual evoked potentials in central demyelinating disorders, non demyelinating disorders and control. BAEP studies showed prolonged inter peak latency in demyelinating diseases when compared to non demyelinating diseases. Among those with discernible SSEP waves (N20, P37), no statistically significant differences were seen between the three groups for both latencies as well as amplitudes of waves. The P 100 wave latency in VEP in demyelinating diseases was more prolonged compared to non demyelinating diseases. The findings showed abnormal evoked potentials in both the groups and they help in early and preclinical diagnosis of central nervous system disorders.

Keywords

Visual Evoked Potential, Ssep, Somatosensory Evoked Potential, Baep-brainstem Evoked Potential, Ipl, Inter Peak Latency
Subscription Login to verify subscription
User
Notifications
Font Size


  • Keith H.Chiappa. Evoked potentials in clinical medicine: Lippincott- Raven. 1997; 1: 1-30.

  • Kerry H Levin, Hans O Luders. Comprehensive clinical neurophysiology : W B Saunders. 2000; 36: 507-564.

  • Misra UK, Kalitha J: Clinical neurophysiology: Elsevier: 2005; 8:257

  • Pal GK, Pravati Pal: Text book of practical physiology: Orient Longman: 2005;41: 305-309.

  • Keith H.Chiappa, Rosamund A. Hill. Evoked potentials in clinical medicine: Lippincott- Raven. 1997; 3: 95-105

  • Ronald G Emerson. Comprehensive clinical neurophysiology: W B Saunders. 2000; 38, 543-564.

  • Bradley WG,Robert D Daroff.Neurology in clinical practice :Elsevier. 2008. 5th ed.;58:1583

  • Keith H. Chiappa, Rosamund . Evoked potentials in clinical medicine: Lippincott –Raven . 1997; 6: 222-225.

  • Mani J, Chaudary N Ravats, Shah PU. Multiple Sclerosis : Experience in neuron imaging era from western India. Neural India.1999; 47: 8-11.

  • Misra UK , Kalitha J. Clinical neurophysiology:Elsevier:2005;10:279

  • Despland PA, Regli F. Somatosensory evoked response changes in potential with unilateral vascular lesions In: Morocutti c,Rizzo PA,(eds)Evoked potential Neurophysiological and clinical aspects.Elsevier,Newyork .1985;57.

  • Nightingale S, Mitchell K W, Howe JW. Visual evoked potentials and pattern electroretinograms in Parkinson’s disease and control subjects. J Neurol Neurosurg Psychiatry. 1986 Nov; 49(11):1280-7.


Abstract Views: 253

PDF Views: 0




  • Study of Evoked Potentials in Central Demyelinating Disorders Versus Nondemyelinating Disorders

Abstract Views: 253  |  PDF Views: 0

Authors

P Prabhakar
Associate Professor, Department of Physiology, Sree Mookambika Medical College & Research Institute, Kulasekharam, Kanyakumari
Girwar Singh Gaur
Additional Professor, Department f Physiology
Sunil K Narayanan
Professor, Department of Neurology, JIPMER, Pondicherry

Abstract


We studied brainstem auditory, somatosensory and visual evoked potentials in central demyelinating disorders, non demyelinating disorders and control. BAEP studies showed prolonged inter peak latency in demyelinating diseases when compared to non demyelinating diseases. Among those with discernible SSEP waves (N20, P37), no statistically significant differences were seen between the three groups for both latencies as well as amplitudes of waves. The P 100 wave latency in VEP in demyelinating diseases was more prolonged compared to non demyelinating diseases. The findings showed abnormal evoked potentials in both the groups and they help in early and preclinical diagnosis of central nervous system disorders.

Keywords


Visual Evoked Potential, Ssep, Somatosensory Evoked Potential, Baep-brainstem Evoked Potential, Ipl, Inter Peak Latency

References