Indian Journal of Science and Technology

Open Access Open Access  Restricted Access Subscription Access

Aquatic Toxicity of Dimethyl Sulphoxide on the Indian Major Carp, Catla catla (Hamilton)


Affiliations
1 Department of Zoology, Sir Thyagaraya College, Chennai-600 021, India
2 Department of Chemistry, Loyola College, Chennai-600 034, India
 

DMSO is frequently used as carrier solvent in toxicological experiments due to its exceptionally low toxicity and environmental impact and also to achieve more effective dispersion of the toxicants. Aquatic toxicity studies of DMSO on the respiratory rates and the biochemical constituents of muscle and liver in catla revealed minimal lethality and negligible effect on the physiology of the test organism. This study helps in the choice of percentage of the carrier solvent that can be used in the preparation of toxicants for any toxicological studies involving fish.

Keywords

Aquatic Toxicity, Dimethyl Sulphoxide, Catla catla
User

  • Anon (1984) Water quality management in aquaculture, (CMFRI Special publication No.22). CMFRI, Cochin.

  • Bhttacharya S (2001) Stress response to pesticides and heavy metals in fish and other vertebrates. Proc Indian Nat Acad (Part B). 673, 215-246.

  • Carrol WV, Longley RW and Roe JH (1956) The determination of glycogen in the liver and muscle by the use of Anthrone reagent. J Biol Chem. 220, 583-593.

  • Dhanapakiam P and Ramasamy VK (2001) Toxic effects of copper and zinc mixtures on some haematological and biochemical parameters in common carp, Cyprinus carpio (Linn.). J Environ Biol. 22, 105-116.

  • Hutchinson TH, Shillabeer N, Winter MJ and Pickford DB (2006) Acute and chronic effects of carrier solvents in aquatic organisms:A critical review. Aquatic Toxicology. 76, 69-92.

  • Jayaraman J (1988) (Bligh and Dyer method), in Laboratory Manual in Biochemistry (Willey Eastern Ltd). New Delhi, 96.

  • Johannesson H, Denisov VP and Halle B (1997) Dimethyl sulfoxide binding to globular proteins: A nuclear magnetic relaxation dispersion study. Protein Sci. 6, 1756-1763.

  • Kumar S and Singh M (2000) Toxiciy of dimethoate to a freshwater teleost, Catla catla (Ham.). J .Exp. Biol. 3, 83-88.

  • Lowry OH, Rosebrough NJ, Farr AL and Randall RJ (1951) Protein measurement with folin phenol reagent. J. Biol. Chem. 193, 265- 275.

  • Mathivanan R (2004) Effects of sublethal concentration of quinalphos on selected respiratory and biochemical parameters in the freshwater fish, Oreochromis mossambicus. J. Ecotoxicol. Environ. Moni. 14, 57-64.

  • Meha B, Vankhede GN and Dhande RR (2004) Heavy metal induced Biochemical alterations in the freshwater fish Labeo rohita. J Ecotoxicol Environ Moni. 14, 1-7.

  • Mortensen AS and Arukwe A (2006) Dimethyl sulfoxide is a potent modulator of estrogen receptor isoforms and xenoestrogen biomarker responses in primary culture of salmon hepatocytes. Aquatic Toxicology. 79, 99-103.

  • Nanda PL, Nath DP and Behera KM (2002) Respiratory metabolism of fish Oreochromis mossambicus (Peters) exposed to pulp and paper mill effluents. Env. Eco. 20, 570-572.

  • Omprakasam M and Manohar L (1991) Experimental infection of some bacterial fish pathogens in the cichlid fish, Oreochromis mossambicus. Indian J Fish. 38, 106-110.

  • Santhakumar M and Balaji M (2000) Acute toxicity of an organophosphorus insecticide monocrotophos and its effects on behaviour of an air breathing fish Anabas testudineus (Bloch). J. Environ. Biol. 21, 121-123.

  • Shrivastava S and Singh S (2004) Changes in protein content in the muscle of Hetropneustes fossilis exposed to carbaryl. J. Ecotoxicol. Environ. Monit.14, 119-122.

  • Sujatha LB (2006) Studies on the physiology, haematology and histopathology in the Indian Major Carp, Catla catla (Hamilton), as influenced by individual and synergistic toxic effects of a pesticide and two metallic compounds. Ph.D. thesis, University of Madras.

  • Tilak KS, Satyavardhan K and Thathaji PB (2003) Biochemical changes induced by fenvalerate in the freshwater fish Channa punctatus. J. Ecotoxicol. Environ. Monit. 13,261-270.

  • Willford WA (1967) Toxicity of dimethyl sulfoxide to fish, in Investigations in fish control (Resource publication) United States Bureau of Sport Fisheries and Wildlife. No.37 8p.

  • Yang R, Brauner C, Thurston V, Neuman J and Randall DJ (2000) Relationship between toxicant transfer kinetic processes and fish oxygen consumption. Aqua. Toxicol. 48, 95- 108.


Abstract Views: 385

PDF Views: 88




  • Aquatic Toxicity of Dimethyl Sulphoxide on the Indian Major Carp, Catla catla (Hamilton)

Abstract Views: 385  |  PDF Views: 88

Authors

M. Omprakasam
Department of Zoology, Sir Thyagaraya College, Chennai-600 021, India
A. Dayalan
Department of Chemistry, Loyola College, Chennai-600 034, India
M. Arul Ganesan
Department of Chemistry, Loyola College, Chennai-600 034, India

Abstract


DMSO is frequently used as carrier solvent in toxicological experiments due to its exceptionally low toxicity and environmental impact and also to achieve more effective dispersion of the toxicants. Aquatic toxicity studies of DMSO on the respiratory rates and the biochemical constituents of muscle and liver in catla revealed minimal lethality and negligible effect on the physiology of the test organism. This study helps in the choice of percentage of the carrier solvent that can be used in the preparation of toxicants for any toxicological studies involving fish.

Keywords


Aquatic Toxicity, Dimethyl Sulphoxide, Catla catla

References





DOI: https://doi.org/10.17485/ijst%2F2008%2Fv1i4%2F29239