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An Overview of Biomedical Materials and Techniques for Better Functional Performance, Life, Sustainability and Biocompatibility of Orthopedic Implants


Affiliations
1 Mechanical Engineering, Chandigarh University, Mohali-140413, Punjab, India
2 Department of Mechanical Engineering, Y.C.O.E, Punjabi University, Patiala-151302, Punjab, India
 

Objectives: Improvement in the functional performance and biocompatibility of biomedical implants using different bioactive materials and coating techniques. Methods/Statistical Analysis: The requirement of bio activity, biocompatibility with proficient mechanical properties without immune rejection for long lasting implants and bone substitutes is a tremendous challenge. These bone substitute structures ought to be set up for individual patients with all details controlled on the micrometer level. Findings: The metallic implants (Ti-alloys, Co-alloy and Stainless steel) utilized by researchers to investigate bone fractures and imperfections are unsuccessful to perform in biomedical applications as they failed to build required bond with living bone. The scientists proposed combining the bio activity of bioactive materials and excellent mechanical properties of metals by depositing bio active materials on metal base material. Application/Improvements: Many methods like plasma spraying, thermal spraying, pulsed laser ablation, sputter coating, etc., were utilized to efficiently coat bioactive materials on metal base. In this paper, we will review the bioactive materials including different methods utilized in depositing bio-ceramics and effect of cryogenic processing on biomedical implants.
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  • Fernandez J, Gaona M, Guilemany JM. Effect of heat treatments on HVOF hydroxyapatite coatings. Journal of Thermal Spray Technology. 2007; 16(2):220–28. https://doi.org/10.1007/s11666-007-9034-7
  • Hanawa T. Materials for metallic stents. Journal of Artif Organs. 2009; 12(2):73–9. https://doi.org/10.1007/s10047-008-0456-x PMid:19536623
  • Aksakal B, Gavgali M, Dikici B. The relationship between surface treatments and corrosion resistance of hot-dip galvanized steel. Journal of Material Engineering Perform. 2010; 19(6):894. https://doi.org/10.1007/s11665-009-9559-7
  • Lia H, Khora KA, Cheangb P. Biomaterials. 2002; 23.
  • Sun L, Berndt CC, Gross KA, Kucuk A. Material fundamentals and clinical performance of plasma‐sprayed hydroxyapatite coatings: A review. Journal of Biomedical Materials Research. 2001; 58:570. https://doi.org/10.1002/ jbm.1056 PMid:11505433
  • Mansur MR, Wang J, Berndt CC. Microstructure, composition and hardness of laser assisted Hydroxyapatite and Ti-6Al-4V composite coatings. Surface Coatings Technology. 2013; 232:482–8. https://doi.org/10.1016/j.surfcoat.2013.06.006
  • Pei X, Wang J, Wan Q, Kang L, Xiao M, Bao H. Functionally graded carbon nanotubes/hydroxyapatite composite coating by laser cladding. Surface Coatings Technology. 2011; 205(19):4380–7. https://doi.org/10.1016/j.surfcoat. 2011.03.036
  • Zhou H, Lee J. Nanoscale hydroxyapatite particles for bone tissue engineering. Acta Biomater. 2011; 7(7):2769–81. https://doi.org/10.1016/j.actbio.2011.03.019 PMid:21440094
  • Roy M, Vamsi Krishna B, Bandyopadhyay A, Bose S. Laser processing of bioactive tricalcium phosphate coating on titanium for load-bearing implants. Acta Biomater. 2008; 4(2):324–33. https://doi.org/10.1016/j.actbio.2007.09.008 PMid:18039597
  • Overgaard S, Bromose U, Lind M, Bunger C, Soballe K. The influence of crystallinity of the hydroxyapatite coating on the fixation of implants. Mechanical and histomorphometric results. The Journal of Bone and Joint Surgery. British. 1999; 81(4):725–31.
  • Guo HB, Miao X, Chen Y, Cheang P, Khor KA. Characterization of hydroxyapatite– and bioglass–316L fibre composites prepared by spark plasma sintering. 2004; 58(3-4).
  • Karin Hing A, Peter Revell A, Nigel Smith, Thomas Buckland, Effect of silicon level on rate, quality and progression of bone healing within silicate-substituted porous hydroxyapatite scaffolds. Biomaterials. 2006; 27(29):1-5014.
  • Morks MF. Development of ZrO2/SiO2 bioinert ceramic coatings for biomedical application. Journal of the Mechanical Behavior of Biomedical Materials. 2008; 1:1-105. https://doi.org/10.1016/j.jmbbm.2007.09.002 PMid:19627781
  • Shirtliff VJ, Hench LL. Bioactive materials for tissue engineering, regeneration and repair. Journal of Materials Science. 2003; 38:4697-707. https://doi.org/10.1023/A:1027414700111
  • Mahmoud Ibrahim Z, Ahmed Sarhan AD, Farazila Yusuf, Hamdi M, Biomedical materials and techniques to improve the tribological, mechanical and biomedical properties of orthopedic implants – A review article. Journal of Alloys and Compounds. 2017; 714:636-67. https://doi.org/10.1016/j.jallcom.2017.04.231
  • Dourandish M, Godlinski D, Simchi A, Firouzdor V. Sintering of biocompatible P/M CoCr-Mo alloy (F-75) for fabrication of porosity-graded composite structures. Materials Science and Engineering. 2008; 472:338–46. https://doi.org/10.1016/j.msea.2007.03.043
  • Helmus MN, Gibbons DF, Cebon D. Biocompatibility: Meeting a Key Functional Requirement of NextGeneration Medical Devices. Toxicol Pathology. 2008; 36(1):70–80. https://doi.org/10.1177/0192623307310949 PMid:18337223
  • Sasikumar Y, Rajendran N. Surface modification and in vitro characterization of Cp-Ti and Ti-5Al-2Nb-1Ta alloy in simulated body fluid. Journal of Materials Engineering and Performance. 2012; 21(10):2177–87. https://doi.org/10.1007/s11665-012-0143-1
  • Yoshikawa H, Tamai N, Murase T, Myoui A. Interconnected porous hydroxyapatite ceramics for bone tissue engineering. Journal of the Royal Society, Interface/the Royal Society. 2009.
  • Bansiddhi A, Dunand DC. Processing of NiTi Foams by Transient Liquid Phase Sintering. Journal of Materials Engineering and Performance. 2011; 20(4-5):511-6. https:// doi.org/10.1007/s11665-010-9827-6
  • Karrholm J, Razaznejad R. Fixation and bone remodeling around a low stiffness stem in revision surgery. Clinical Orthopaedics and Related Research. 2008; 466(2):380–8. https://doi.org/10.1007/s11999-007-0039-9 PMid:18196421 PMCid:PMC2505132
  • Nakano T, Kan T, Ishimoto T, Ohashi Y, Fujitani W, Umakoshi Y. Evaluation of bone quality near metallic implants with and without lotus-type pores for optimal biomaterial design. Material Transaction. 2006; 47(9):2233-9. https://doi.org/10.2320/matertrans.47.2233
  • Balani K. Plasma-sprayed carbon nanotube reinforced hydroxyapatite coatings and their interaction with human osteoblasts in vitro. Biomaterials. 2007; 28(4):618–24 https://doi.org/
  • Morks MF. Development of ZrO2/SiO2 bioinert ceramic coatings for biomedical application. Journal of the Mechanical Behavior of Biomedical Materials. 2008; 1(2):105–11.
  • Magallanes-Perdomo M, Luklinska ZB, De Aza AH, Carrodeguas RG, De Aza S, Pena P. Bone like forming ability of apatite wollastonite glass ceramic. Journal of the European Ceramic Society. 2011; 31:1549–61.
  • Liu Y, Sheng XX, Dan XH, Xiang QJ. Preparation of mica/ apatite glass-ceramics biomaterials. Materials Science and Engineering. 2006; 26:1390–4.
  • Shi D, Jiang G, Bauer J. The effect of structural characteristics on the in vitro bioactivity of hydroxyapatite. Journal of Biomedical Materials Research. 2002; 63(1):71–8.
  • Fu Y, Batchelor AW, Khor KA. Fretting wear behavior of thermal sprayed hydroxyapatite coating lubricated with bovine albumin. Wear. 1999; 230:98-102.
  • Yildirim OS, Aksakal B, Celik H, Vangolu Y, Okur A. An investigation of the effects of hydroxyapatite Coatings on the fixation strength of cortical screws. Medical Engineering and Physics. 2005; 27(3):221–8.
  • Ektessabi AM, Hamdi M. Characterization of calcium phosphate bioceramic films using ion beam analysis techniques. Surface and Coatings Technology. 2002; 153(1):10–5.
  • Leeuwenburgh S, Layrolle P, Barrere F, Bruijnde J, Schoonman J, Blitterswijkvan CA, Gischolar_mainde K. Osteoclastic resorption of biomimetic calcium phosphate coatings in vitro. Journal of Biomedical Materials Research. 2001; 56(2):208–15.
  • Fernandez J, Gaona M, Guilemany JM. Tribological study of plasma hydroxyapatite coatings. Bioceramics. 2004; 16:383–6.
  • Aebli N, Krebs J, Stich H, Schawalder P, Walton P, Schwenke D, Gruner H, Gasser B, Theis JC. In vivo comparison of the osseointegration of vacuum plasma sprayed titanium and hydroxyapatite coated implants. Journal of Biomedical Materials Research. 2003; 66A(2):356–63.
  • Fernandez J, Guilemany JM, Gaona M. High crystallinity degree hydroxyapatite coatings. Conference Proceedings ITSC; 2005. p. 1219–24.
  • Wang H, Eliaz N, Xiangc Z, Hsuc HP, Spectorc M, Hobbs L. Early bone apposition in vivo on plasma-sprayed and electrochemically deposited hydroxyapatite coatings on titanium alloy. Biomaterials. 2006; 27(23):4192–203.
  • Wolke JGC, van der Waerden JPCM, Schaeken HG, Jansen JA. In vivo dissolution behavior of various RF magnetron sputtered Ca-P coating on roughened titanium implants. Biomaterials. 2003; 24:2623–9.
  • Zhang MY, Cheng GJ. Pulsed laser coating of hydroxyapatite/ titanium nanoparticles on Ti-6Al-4V substrates: multiphysics simulation and experiments. NanoBioscience. 2011; 10(3):177–86.
  • Yoshinari M, Ohshiro Y, Derand T. Biomaterials. 1994.
  • Shi D, Jiang G, Bauer J. The effect of structural characteristics on the in vitro bioactivity of hydroxyapatite. Journal of Biomedical Materials Research. 2002; 63:1–71.
  • Manso M, Langlet M, Jimenez C, Martinez-Duart JM. Microstructural study of aerosol-gel derived hydroxyapatite coatings. Biomolecular Engineering. 2002; 19(6):63–6.
  • Bigi A, Fini M, Bracci B, Boanini E, Torricelli P, Giavaresi G, Aldini N.N, Facchini A, Sbaiz F, Giardino R. The response of bone to nanocrystalline hydroxyapatite-coated Ti13Nb11Zr alloy in an animal model. Biomaterials. 2008; 29(11):1730-6.
  • Wie H, Hero H, Solheim T. Hot isostatic pressing processed hydroxyapatite coated titanium implants light microscopic and scanning electron microscopy investigation. The International Journal of Oral and Maxillofacial Implants. 1998; 13:1–837.
  • De Gischolar_main K, Geesink R, Klein CP. Plasma sprayed coatings of hydroxylapatite. Journal of Biomedical Materials Research. 1987; 21:1375–81.
  • Lombardi AV. Aseptic loosening in total hip arthroplasty secondary to osteolysis induced by wear debris from titaniumalloy modular femoral heads. Journal of Bone and Joint Surgery. 1989; 71(9):1337–42.
  • John Payne Collier. 2018. Available from: https:// en.wikipedia.org/wiki/John_Payne_Collier.
  • Fleming JE, Cornell CN, Muschler GF. Bone cells and matrices in orthopedic tissue engineering. Orthopedic Clinics of North America. 2000; 31(3):357–74.
  • Morscher EW, Hefti A, Aebi U. Severe osteolysis after thirdbody wear due to hydroxyapatite particles from acetabular cup coating. The Journal of Bone and Joint Surgery. 1998; 80(2):267–72.
  • Melero H, Fargas G, Garcia-Giralt N, Fernandez J, Guilemany JM, Mechanical performance of bioceramic coatings obtained by high-velocity oxy-fuel spray for biomedical purposes. Surface and Coatings Technology. 2014; 242:92–9
  • DeJong ES, DeBeradino TM, Brooks DE. Antimicrobial efficacy of external fixator pins coated with a lipid stabilized hydroxyapatite/chlorhexidine complex to prevent pin track infection in a goat model. The Journal of Trauma and Acute Care Surgery. 2001; 50(6):1008–14.
  • Magyar G, Toksvig-Larsen S, Moroni A. Hydroxyapatite coating of threaded pins enhances fixation. Journal of Bone and Joint Surgery. 1997; 79(3):487–9.
  • Niinomi N. Recent titanium R&D for biomedical applications in Japan. JOM. 1999; 51(6):32–4.
  • Pu Z, Umbrello D, Dillon Jr OW, Lu T, Puleo DA, Jawahir IS. Finite element modeling of microstructural changes in dry and cryogenic machining of AZ31B magnesium alloy. Journal of Manufacturing Processes. 2014; 16:33543.
  • Balusamy T, Kumar S, Narayanan TS. Effect of surface nanocrystallization on the corrosion behaviour of AISI 409 stainless steel. Corrosion Science. 2010; 52:3826–34.
  • Kaynak Y, Tobe H, Noebe RD, Karaca HE, Jawahir IS. The effects of machining on the microstructure and transformation behavior of NiTi Alloy. Scripta Materialia. 2014; 74:60–3.

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  • An Overview of Biomedical Materials and Techniques for Better Functional Performance, Life, Sustainability and Biocompatibility of Orthopedic Implants

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Authors

Parvinkal Singh
Mechanical Engineering, Chandigarh University, Mohali-140413, Punjab, India
Pardeep Kumar
Department of Mechanical Engineering, Y.C.O.E, Punjabi University, Patiala-151302, Punjab, India

Abstract


Objectives: Improvement in the functional performance and biocompatibility of biomedical implants using different bioactive materials and coating techniques. Methods/Statistical Analysis: The requirement of bio activity, biocompatibility with proficient mechanical properties without immune rejection for long lasting implants and bone substitutes is a tremendous challenge. These bone substitute structures ought to be set up for individual patients with all details controlled on the micrometer level. Findings: The metallic implants (Ti-alloys, Co-alloy and Stainless steel) utilized by researchers to investigate bone fractures and imperfections are unsuccessful to perform in biomedical applications as they failed to build required bond with living bone. The scientists proposed combining the bio activity of bioactive materials and excellent mechanical properties of metals by depositing bio active materials on metal base material. Application/Improvements: Many methods like plasma spraying, thermal spraying, pulsed laser ablation, sputter coating, etc., were utilized to efficiently coat bioactive materials on metal base. In this paper, we will review the bioactive materials including different methods utilized in depositing bio-ceramics and effect of cryogenic processing on biomedical implants.

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DOI: https://doi.org/10.17485/ijst%2F2018%2Fv11i28%2F130789