Potency of Sandfish (Holothuria scabra) Powder to Increase Sperm Quality and Sperm Quantity in Mice (Musmusculus)

Objectives: This research is aimed to examine the effect of sandfish powder on the spermatozoa quality and genital weights of male mice. Methods/Analysis: In this study, laboratory experimental method was applied. Male mice were treated by giving sandfish powder in three dosage rates of its steroid content (10, 30, and 50μg of steroid/100g body weight) in 12 days. Whereas for control treatments as well as for comparison, the author utilizes some mature male mice without given any hormone (negative control) and some mature male mice that given methyl testosterone. Findings: The authors examined the quality of spermatozoa (concentration, normality, and motility of spermatozoa) and genital weight (testis and seminal vesicle weight) of each male mouse. It was discovered that administration of sandfish powder did not significantly affect its genital weights as well as normality and motility of the spermatozoa. However, it could increase the concentration of spermatozoa in administration of 10μg of steroid/100g body weight. Application/Improvements: The potential of sandfish powder as drug to enhance the quality of the male reproduction.