Neuroendocrinal Mechanisms of Adaptation to Sports Physical Loads

Objectives: The article is aimed at research of somatotropic function of boys’ pituitary gland and adrenal cortex in a state of relative rest and under physical load for adequate and complete assessment of their functional capabilities. Methods: Functional capabilities of somatotropic pituitary gland function were examined using PWC170 test. The level of activity of pituitary gland and adrenal cortex was examined by radioimmunoassay technique before the load and in 15 and 45 minutes after the load. The results were statistically processed according to the Student-Fisher variation, statistic technique and rank correlation method, the variability of parameters was assessed by means of the variability coefficient. Findings: To determine the functional reserve of pituitary gland and growth capabilities of the body, a comparative assessment of somatotropin dynamics was made in the state of relative rest and under various loads. The following results have been achieved: comparative assessment of pituitary gland response under different kinds of physical load, identification of its peculiarities, characteristics of general rules of pituitary gland response to the examined loads on boys in the course of somatic growth, simultaneous examination of the response of pituitary gland (with respect to somatotropin) and adrenal cortex (with respect to cortisol) under various loads. This paper shows that pituitary gland activity increases under physical load with PWC170 power. Pituitary gland response in the 45th minute is more significant than response in the 15th minute after the load. In each specific case, the trend of response (increase or decrease), incremental value of somatotropin and the rate of response were subject to the value of the initial level of pituitary gland activity. Application: This article is of practical value for hormonal therapy.