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Authors
Source
NIMHANS Journal, Vol 15, No 2 (1997), Pagination: 177-180
Abstract
Guillain - Barre syndrome (GBS) is an immune mediated acute polyradiculopathy of undetermined etiology. A range of probable etiological agents such as viruses, bacteria, malignancy, surgery etc. have been suspected for the condition. In view with the endemicity of mycobacterial infections an attempt has been made to look for antimycobacterial immune response in the serum of patients with GBS. Anti-Mycobacterial antibodies of both IgG and IgM type are significantly high in serum of GBS than in controls (p<0.05). Immune complexes which generally reveal the acute phase of infection were absent both in GBS and controls. The study indicates the probability of chronic association of mycobacterial infection in GBS cases.
Keywords
Guillain Barre' Syndrome, Mycobacteria, Antibodies, Immune Complexes
