Abstract Views :196 |
Authors
Source
NIMHANS Journal, Vol 6, No 2 (1988), Pagination: 145-149
Abstract
Two hundred seventy five potential recruits to a double blind clinical trial comparing the efficacy of alprazolam with diazepam and imipramine in generalized anxiety disorder and major depression respectively were provided information about the trial in a standard manner. Except two subjects all others expressed clear choice about their participation. 62% of the subject consented for the trial, 37% refused for various reasons. Two subjects expected the treating doctor to decide for them. 15% of the subjects asked for further details before giving their choice. Comparison of the consenting and non-consenting subjects did not reveal any significant differences with respect to socio-demographic and clinical variables. The findings suggest that patients can express clear choice for drug trial provided sufficient information is given to them for making a choice.
Keywords
Informed Consent, Drug Trial
