Indian Journal of Public Health Research & Development

Shruthi Parthasarathy ¹, Sarumathi Thirugnanamurthy ¹, A. Amudhan ¹, V. T. Hemalatha ¹, T. Manigandan ¹

Affiliations
1 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital BIHER, Chennai, IN

Abstract

The prescription of antibiotics is reaching its peak day by day in all specialities. This is causing antibiotic resistance in many bacteria along with evolution of newer multiple drug resistant strains of bacteria. If this situation continues then we would tend to ‘lose battle against the bugs’. Dentistry is a speciality commonly prescribing antibiotics all over the world. Lack of proper knowledge and lethargic attitude of many dentists contribute largely to the increasing antibiotic resistance among patients.

Keywords

Antibiotics, Bacterial Resistance, Dentistry.

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R. Bhargavi ¹, V. T. Hemalatha ¹, A. Amudhan ², T. Sarumathi , T. Manigandan

Affiliations
1 Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN
2 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN

Abstract

Being the most common medical professionals in prescribing of Non-steroidal anti- inflammatory medications, Dentist in India are to be essentially aware of banned medications, that due to various reasons, still haven’t been withdrawn from market. Many fixed drug combinations are easily available without any scientific justification behind them. This article aims in creating an awareness among the dentist regarding banned fixed drug combinations of NSAIDS in India since September 2018.

Keywords

Banned drugs, NSAIDs, Fixed Drug Combinations. Corresponding Author:

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H. Aravindhswamy ¹, R. Sankar Narayanan ¹, T. Manigandan ¹, Nalini Aswath ¹, V. T. Hemalatha ²

Affiliations
1 Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN
2 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN

Abstract

Pharmacovigilance is useful toreassure the safety of drugs and protecting the consumers from their injuries effects. A number of single drugs as well as fixed dose combinations have been banned from manufacturing, marketing and distribution in India. An important issue about the availability of banned drugs over the counter in India is that sufficient adverse drug reactions data about these drugs have not been reported. The most common categories of drugs withdrawn in the last decade were non steroidal anti inflammatory drugs (28%), antidiabetics (14.28%), antiobesity (14.28%), antihistamines (14.28%), gastroprokinetic drugs (7.14%), breast cancer and infertility drugs (7.14%), irritable bowel syndrome and constipation drugs (7.14%) and antibiotics (7.14%). Drug withdrawals from market were made mainly due to safety issues involving cardiovascular events (57.14%), liver damage (14.28%), and carcinogenic reasons . Majority of drugs have been banned since 3-5 years in other countries but are still available for sale in India. The present study says about how to manage adverse drug reactions and to prevent it in advance and provides implications for developing a system that can ensure the safety and efficacy of drugs in India.There should be a multidisciplinary approach towards drug safety that should be implemented throughout the entire duration spanning from drug discovery to usage by consumers.

Keywords

Pharmacovigilance, Adverse Drug Reaction, Drug Safety, Multidisciplinary Approach.

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Jemima Judith ¹, T. Manigandan ¹, T. Sarumathi ¹, A. Amudhan ¹, Nalini Aswath ²

Affiliations
1 Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN
2 Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Chennai, Tamil Nadu, IN

Abstract

Immune-mediated diseases are some of the diseases that affect the patient’s quality of daily life due to their chronic nature. Of which most of them are mucocutaneous diseases and they involve the oral cavity. The treatment of these diseases is oftentimes challenging due to their immunological nature, comorbidity, frequent relapses and long term use of medications and their complications. Immunomodulators are the most rapidly developing current trend. They are used quite often for a large number of these diseases. This article discusses some of the lesions where immunomodulatory drugs are used.

Keywords

Immunomodulators, Immunosuppressants, Immunostimulants.

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M. Jemima Judith ¹, T. Manigandan ²

Affiliations
1 Post Graduate Student, Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Tamil Nadu, Chennai, IN
2 Professor, Department of Oral Medicine and Radiology, Sree Balaji Dental College and Hospital, BIHER, Tamil Nadu, Chennai, IN

Abstract

Conventional radiation therapy is one of the most common methods of cancer treatment. Because of conventional therapy’s early and late toxicity, it is of great interest to find a modality that has low side effects to the normal tissues. This has led to the invention of proton therapy. Proton therapy is believed to have better results than conventional radiotherapy. Proton beam therapy is a recent modality that is more tumour conservative than photon beam therapy. The physical property of protons spares the normal surrounding tissues. More clinical trials and prospective studies are required for the inclusion of proton therapy in treating carcinomas of the head and neck.

Keywords

Radiation, Photon Therapy, Computed Tomography.

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