Open Access
Subscription Access
Open Access
Subscription Access
A Study of Management of Periodontal Osseous Defects with Xenograft and Bioresorbable Membrane
Subscribe/Renew Journal
Recent research has focused upon use of bone substitutes in combination with the GTR barriers for better clinical outcomes of periodontal regenerative procedures.The purpose of this study was to evaluate the efficacy of bovine derived xenograft (Bio-Oss) and bioresorbable GTR membrane (Atrisorb) in interproximal vertical Defects.
Two systemically healthy patients (1 male,1 female) were selected with 12 sites each. Sites were assigned randomly into control (flap debridement Plus Bio-Oss)and experimental( flap debridement plus Bio-Oss and Atrisorb). Clinical measurements included plaque index (PI), gingival index (GI), probing pocket depth (PPD), Clinical attachment level (CAL), gingival margin position (GMP). Statistical Analysis was performed using the paired and unpaired 't' tests.
In the results, the control and experimental group showed statistically highly significant (p<0.001) Changes in GI, PPD and CAL 9 months post surgery. Between the groups statistical significance was not found in all clinical Parameters. Radiographic measurements showed a statistically highly significant Amount of defect fill in individual in each group and between the groups.
In this study the combined use of GTR barrier and bone graft did not prove beneficial Over the bone graft alone for the clinical outcome of interproximal vertical defect treatment.
Keywords
- The American Academic of Periodontology, 4th ed, Chicago; 2001: 44.
- Carranza FA Jr. And Newman MG, Glickman’s Clinical Periodontology, Philadelphia, WB Sauders, 1996; 269-278.
- Guillemin MR, Mellonig JT and Brunswold MA. Healing in periodontal defects treated by decalcified freeze-dried bone allografts in combination with e-PTFE membranes. Clinical and scanning electron microscope analysis. J. Clin Periodontol 1993; 20: 528-536.
- Lekovic V. Kenney EB, Carranza FA Jr. And Danilovic V. Treatmetn of class II furcation defexts using porous hydroxyapatite in conjunction with a polytetrafluoroethylene membrane. J Periodontol 1990; 61:575-578.
- Gottlow, J. Lang NP and Karring T. Periodontal regeneration. Proceedings of the 1st European Workshop in Periodontology, 1994; 162-192.
- Lekovic V, Camargo PM, Weinlaender M, Kenney EB and Vasilic N. Combination use of Bovine porous bone mineral, enamel matrix proteins, and a bioabsorbable membrane in intrabony periodontal defects in humans. J. Periodontol 2001; 72:583-589.
- Stavropoulos A, Karring ES, Kostopoulos L and Karring T. Deproteinized bovine bone and gentamicin as an adjunct to GTR in the treatment of intrabony defects: a randomized controlled clinical study. J Clin Periodontol 2003; 30: 486- 495.
- Richardson CR, Mellonig JT and Brunsvold MA. Clinical evaluation of Bio-oss a bovine derived xenograft for the treatment of periodontal osseous defects in humans. J. Clin Periodontol 1999; 26: 421-428.
- Hutchens L. The use of a bovine bone mineral in periodontal osseous defects. Case reports. Periodont Abstr 1999; 47:53
- Bower RC. Furcation morphology relative to periodontal treatment furcation entrance architecture. J Periodontol 1989; 50:23-27.
- Lekovic V, Camargo PM, Weinlaender M, Nedic M, Aleksic Z and Kenney BE. A controlled reentry study on effectiveness of bovine porous bone mineral used in combination with a collagen membrane of porcine origin in the treatment of infrabony defects in humans. J Clin Periodontol 2000; 27 (Supplemental I): 30.
- Mellonig JT. Human Histologic evaluation of a bovine-derived hone xenograft in the treatment of periodontal osseous defects. Int. J Periodont Rest Dent 2000; 20: 19-29.
- Vouros I, Aristodimou E and Konstantinidis A. Guided tissue regeneration in intrabony periodontal defects following treatment with two bioabsorbable membranes in combination with bovine bone mineral graft. A Clinical and radiographic study. J Clin Periodontol 2004; 31: 908-917.
Abstract Views: 368
PDF Views: 0