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A Study on Risk Factors of Type-2 Diabetes Mellitus - a Case Control Study


Affiliations
1 Department of Community Medicine, J J M Medical College, Davangere, Karnataka, India
2 Department of Community Medicine, S S I M S & R C, Davangere, Karnataka, India
     

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Background: According to WHO estimates, India will be the global capital of Diabetes by 2030, accounting for about 79.4 million diabetics. Type 2 DM is one of the most common health problems in India. It is caused by the interaction of multiple risk factors, which may be constitutional, behavioral or environmental factors. Identification of these risk factors is important in order to prevent or postpone the development of the disease.

Objectives: To identify the risk factors of type 2 DM and to study the association of risk factors and the strength of the association with the occurrence of type 2 DM. Methods: Cross-sectional, hospital based case-control study conducted at Chigateri General Hospital and Bapuji Hospital, both teaching hospitals of J.J.M. Medical College, Davangere, Karnataka. Study was carried out from November 2010 to October 2011.

Results: This study comprises of 406 cases and 406 controls. Positive family history (OR-1.6), alcohol intake (OR-1.5), decreased physical activity (OR-2.8), lack of exercise (OR-1.7) and obesity (OR-2.5) were identified as independent risk factors for type 2 DM. By multivariate analysis all the above factors were found to be significant with p values 0.02, 0.07, 0.00, 0.00 and 0.00 respectively.

Conclusion: Type 2 DM can be prevented or postponed by early detection of risk factors and modifications in life style and behavioral patterns.


Keywords

Type 2 Diabetes Mellitus, Risk Factors, Case-control Study
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  • WHO, Diabetes Action Now Booklet;Geneva;2004:8
  • Bulletin of World Health Organization; 2004; 82; 7:556.
  • WHO, Prevention and control of diabetes mellitus. Report of an Intercountry Workshop. Dhaka. Bangladesh; 1998:27-30.
  • WHO, Diet, Nutrition and Prevention of Chronic Diseases. Technical Report Series 916; Geneva; 2003: 248.
  • Ramaiah KL, Kodal VRR, Albert KGMM. Epidemiology of Diabetes in Asians and Indian subcontinent, Diabetes metabolism review; 1990; 6:125-146.
  • Krentz A J, Bailey JC. Type 2 Diabetes in practice, (in practice series); 2001: 4.
  • Wild S, Sicree R, Roglic G, King H, Green I. Global prevalence of diabetes, Estimates for the year 2000 and projections for 2030. Diabetes care, 2004; 27; 5: 1050.
  • Ramachandran A, Snehalatha, Latha E, Vijay V, Vishwanathan M. rising prevalence of NIDDM in urban population in India. Diabetologia 1997; 40:232-237.
  • WHO, Health situation in the South-East Asia Region 1998-2000, New Delhi; 2002: 48.
  • Maty SC, Everson-Rose SA, Haan MN, Raghunathan TE, Kaplan GA. Education, Income, Occupation and the 34year incidence (1965-99) of type 2 diabetes in the Alameda County Study. Int.J.Epid; 2005; 34(6): 1274-1281.
  • PanCY, Lu JM, Tian H, Kong XT, Lu XP, Yao C et al. Study of the Prevalence of Diabetes Mellitus in adults in the Shougang Corporation in Beijing. Diabet.Med; 13(7): 663-668.
  • Banerjee P, Ghosh MM, Biswas R, Bhattacharya SK. A Study of risk factors of diabetes mellitus, Indian Journal of Community Medicine; 1993; 18; 1:48-50.
  • Ramachandran A. Type 2 Diabetes, A growing menace in India; Type 2 Diabetes, the India scenario; 1st edition; 2002: 24.
  • Krentz A J, Bailey JC. Type 2 Diabetes in practice (in practice series); 2001:3.
  • Meyer KA. Dietary fat and incidence of type 2 diabetes in older lowa women. Diabetes care; 2001; 24:1528-1535.
  • Carlsson S, Hammar N, Efendic S, Person PG, Ostenson CG, Grill V. Alcohol consumption, type 2 DM and impaired glucose tolerance in middle aged Swedish men. Diabetes Medicine; 2000; 17:777-781.
  • Perry IJ, Wannamethee SG, Walker MK, Thomson AG, Whincup PH, Shaper AG. Prospective study of risk factors for development of non-insulin dependent diabetes in middle-aged British men. BMJ; 1995; 310:560-564.
  • Lindstrom J, Louheranta A, Mannelin H, Rartas H, Salminen V, Eriksson J et al. The Finnish Diabetes Prevention study (DPS) lifestyle intervention and 3year study on diet and physical activity. 2003; 26:3230-3236.
  • Manson JE, Rimm EB, Stampfer MJ, Colditz GA, Willett WC, Krolewrlci AS, Rosner B et al. Physical activity and incidence of non-insulin dependent diabetes mellitus in women.1991; 338(8770): 774-778.
  • WHO, Diet, Nutrition and Prevention of Chronic Diseases. Technical Report Series 916; 2003: 246.
  • Rimm EB, Manson JE, Stampfer MJ, Colditz GA, Willett WC, Rosner B et al. Oral contraceptive use and the risk of type 2 (non-insulin dependent) diabetes mellitus in a large prospective study of women. Diabetologia; 1992; 35; 10:967-972.

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  • A Study on Risk Factors of Type-2 Diabetes Mellitus - a Case Control Study

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Authors

G.S. Vidya
Department of Community Medicine, J J M Medical College, Davangere, Karnataka, India
A H Suryakantha
Department of Community Medicine, S S I M S & R C, Davangere, Karnataka, India

Abstract


Background: According to WHO estimates, India will be the global capital of Diabetes by 2030, accounting for about 79.4 million diabetics. Type 2 DM is one of the most common health problems in India. It is caused by the interaction of multiple risk factors, which may be constitutional, behavioral or environmental factors. Identification of these risk factors is important in order to prevent or postpone the development of the disease.

Objectives: To identify the risk factors of type 2 DM and to study the association of risk factors and the strength of the association with the occurrence of type 2 DM. Methods: Cross-sectional, hospital based case-control study conducted at Chigateri General Hospital and Bapuji Hospital, both teaching hospitals of J.J.M. Medical College, Davangere, Karnataka. Study was carried out from November 2010 to October 2011.

Results: This study comprises of 406 cases and 406 controls. Positive family history (OR-1.6), alcohol intake (OR-1.5), decreased physical activity (OR-2.8), lack of exercise (OR-1.7) and obesity (OR-2.5) were identified as independent risk factors for type 2 DM. By multivariate analysis all the above factors were found to be significant with p values 0.02, 0.07, 0.00, 0.00 and 0.00 respectively.

Conclusion: Type 2 DM can be prevented or postponed by early detection of risk factors and modifications in life style and behavioral patterns.


Keywords


Type 2 Diabetes Mellitus, Risk Factors, Case-control Study

References