Indian Journal of Medicine and Healthcare

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Microgynon a combined pill (0.15mg levonorgestrel and 0.03mg ethinylestradiol), Primolut-N a mini pill (5mg norethister-one) and Postinor a post coital pill (0.75mg levonorgestrel) were analysed for their Invivo effects on wistar albino rat, plasma total protein. Plasma total protein is a measure of the total amount of proteins in the blood. Studies showed that plasma total protein was decreased by the drugs with Microgynon having the highest decrease (0.57 ± 0.19 g/l) (P < 0.05) followed by Primulot (0.95 ± 0.19 g/l) and then Postinor (1.14 ± 0.19 g/l). The random use of the drugs in our society today especially as most women abuse these drugs demands for more biochemical research to elucidate the effects of these drugs not only on the hormones but also, on other biochemical parameters like the plasma total protein. The obtained results indicate that women should use these drugs only after physicians advice.

Keywords

Microgynon, Primolut-N, Total Protein
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