Indian Journal of Innovations and Developments

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Semecarpus anacardium Linn. is a medicinal plant known for its potent medicinal properties, used in Ayurveda and Siddha, also popularly used in tribal and rural areas of India for treatment of various disorders and gaining immunity. It is known as 'rasayana' and reported in ancient literature that indiscriminate use of nut oil cause ill effects on skin, and eyes. S. anacardium pericarp oil extract (SAE) has commercial importance in preparation of herbal medicines and dyes. Large number of labours from rural areas are involved in extraction of oil, were found suffering from deformities due to exposure. No work was reported yet regarding toxic effects of Semecarpus anacardium. The present work deals with the assessment of effect of SAE on biochemical parameters (Total proteins, glucose, glycogen, cholesterol and Mg) and activity of GOT, GPT, LDH, SDH and AChE enzymes of brain of albino rat. Experimental albino rat after oral treatment of SAE showed alteration in studied parameters indicating the adverse effect on brain compared to control group. Outputs of the study signify the need of safe environment, safer extraction process and a proper training to those workers.

Keywords

Semecarpus anacardium, Albino Rat, Brain Parameters, Toxicity, Environment Safety
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