Objective: To investigate lead nitrate toxicity with emphasis on the histopathological effects of fish Labeorohita.
Methods: The fishes were exposed to 31, 31.5, 32, 32.5 and 33ppm of lead nitrate (LN) solution at 24, 48, 72 and 96 hours of intervals. The lethal conc. (LC50) value of lead nitrate was 33ppm for 96 h of exposure. Fishes were exposed to control and sub lethal conc. of lead nitrate (3.3ppm) over a period of 96 h.
Findings: Histopathology of fish organs, after 96 Hof LN exposure revealed the cell proliferation, lamellar fusion, lamellar cell hyperplasia, and epithelial lifting. The vacuolation of hepatocytes and necrosis were observed in liver. The changes of the tissue cells were predominantly showed in 96hr.
Application/Improvements: LN is highly toxic to Labeorohita therefore its high conc. of LN in areas close to aquatic bodies should not be encouraged. Fishes from such water bodies is not suitable for human consumption because of the possibility of toxic material present in the fish. Fishes as well as water due to such pollution are toxic to human beings.