Seasonal Variation in Hepatoprotective Activity of Titeypati (Artemisia vulgaris L. ) Leaves on Antitubercular Drugs Induced Hepatotoxicity in Rats.

Plant Titeypati (Artemisia vulgaris L.), belongs to the family Asteraceae, is abundant in Sikkim and Darjeeling Himalayas in the middle and upper hill forest up to the height of 2000-5000 ft. Titeypati is a medicinal plant traditionally used to treat a wide range of diseases. Hepatoprotective activity of Titeypati has been noted in hepatotoxicity in rats. Seasonal variation in this effect, if any, was studied. Results showed that Titeypati leaves during the period May - June had maximum protective effect on anti tubercular drugs induced hepatotoxicity in rats.