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In Vitro Comparative Studies of Anthelmintic Activity of Allium sativum and Ficus religiosa


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1 Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
     

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Aqueous extracts of bulb of Allium sativum and bark of Ficus religiosa were taken for anthelmintic activity against Indian earthworm Pheritima posthuma. Three concentrations (25, 50 and 100 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worm. Piperazine citrate (10 mg/ml) was used as a reference standard. Dose dependent activity was observed in both plant extracts but Allium sativum shows more activity as compared to Ficus religiosa. It was concluded that the studied plants had anthelmintic activity. Therefore, in vivo trials may be conducted for further evidence for their use in animals on scientific basis.

Keywords

Anthelmintic Activity, Pheritima posthuma, Aqueous Extracts, Allium sativum, Ficus religiosa.
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  • In Vitro Comparative Studies of Anthelmintic Activity of Allium sativum and Ficus religiosa

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Authors

R. D. Dubey
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
S. Paroha
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
V. K. Wani
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
A. K. Pandey
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
P. K. Sahu
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
S. Verma
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India
S. J. Daharwal
Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, 492101, India

Abstract


Aqueous extracts of bulb of Allium sativum and bark of Ficus religiosa were taken for anthelmintic activity against Indian earthworm Pheritima posthuma. Three concentrations (25, 50 and 100 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worm. Piperazine citrate (10 mg/ml) was used as a reference standard. Dose dependent activity was observed in both plant extracts but Allium sativum shows more activity as compared to Ficus religiosa. It was concluded that the studied plants had anthelmintic activity. Therefore, in vivo trials may be conducted for further evidence for their use in animals on scientific basis.

Keywords


Anthelmintic Activity, Pheritima posthuma, Aqueous Extracts, Allium sativum, Ficus religiosa.