Research Journal of Pharmacology and Pharmacodynamics

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Evaluation of Anti-Hyperglycaemic Activity of Polyherbal Formulation by using In-Vitro Methods


Affiliations
1 St. Mary's College of Pharmacy, Chebrolu, Guntur(DT) Andhra Pradesh, India
2 St. Mary's College of Pharmacy, Chebrolu, Guntur (DT) Andhra Pradesh, India
3 SIMS College of Pharmacy, Guntur Andhra Pradesh, India
4 Dept. of Pharmacology, Siddhartha Institute of Pharmaceutical Sciences, Narsaraopet, Guntur (DT) Andhra Pradesh, India
     

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Diabetes mellitus is a chronic disorder caused by partial or complete insulin deficiency, resulting in hyperglycaemia leading to acute and chronic complications. The incidence of diabetes mellitus is on rise all over the world. Synthetic drugs are likely to give serious side effects in addition they are not suitable for intake during conditions like pregnancy. Hence, search for a new drug with low cost, more potential, without adverse effects is being pursued in several laboratories all around the world. Different extracts of Coriander, Cinnamon and Musa paradisiaca were used for determining antidiabetic activity. In vitro antidiabetic activity was performed by Glucose Diffusion Inhibitory Study. The results showed coriander and cinnamon reported anti-hyperglycemic effects and use of floral extract of banana tree leads to correction of no of secondary complications.

Keywords

Diabetes mellitus, Hyperglycaemia, Coriander, Cinnamon and Musa paradisiaca.
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  • Evaluation of Anti-Hyperglycaemic Activity of Polyherbal Formulation by using In-Vitro Methods

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Authors

I. Srivallika
St. Mary's College of Pharmacy, Chebrolu, Guntur(DT) Andhra Pradesh, India
P. Shivasri
St. Mary's College of Pharmacy, Chebrolu, Guntur(DT) Andhra Pradesh, India
M. Ramesh
St. Mary's College of Pharmacy, Chebrolu, Guntur(DT) Andhra Pradesh, India
P. Jony Basha
St. Mary's College of Pharmacy, Chebrolu, Guntur(DT) Andhra Pradesh, India
T. Vinay Kumar
St. Mary's College of Pharmacy, Chebrolu, Guntur (DT) Andhra Pradesh, India
B. Ram Sarath Kumar
SIMS College of Pharmacy, Guntur Andhra Pradesh, India
D. Rajesh Kumar
Dept. of Pharmacology, Siddhartha Institute of Pharmaceutical Sciences, Narsaraopet, Guntur (DT) Andhra Pradesh, India

Abstract


Diabetes mellitus is a chronic disorder caused by partial or complete insulin deficiency, resulting in hyperglycaemia leading to acute and chronic complications. The incidence of diabetes mellitus is on rise all over the world. Synthetic drugs are likely to give serious side effects in addition they are not suitable for intake during conditions like pregnancy. Hence, search for a new drug with low cost, more potential, without adverse effects is being pursued in several laboratories all around the world. Different extracts of Coriander, Cinnamon and Musa paradisiaca were used for determining antidiabetic activity. In vitro antidiabetic activity was performed by Glucose Diffusion Inhibitory Study. The results showed coriander and cinnamon reported anti-hyperglycemic effects and use of floral extract of banana tree leads to correction of no of secondary complications.

Keywords


Diabetes mellitus, Hyperglycaemia, Coriander, Cinnamon and Musa paradisiaca.

References