Research Journal of Pharmacology and Pharmacodynamics

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Immunostimulatory Activity of Rosa centifolia in Azathioprine Induced Rats


Affiliations
1 PG and Research Department of Biochemistry, S.T.E.T. Women's College, Sundarakkottai, Mannargudi -614001, Tamil Nadu, India
     

   Subscribe/Renew Journal


The ethyl acetate extract of Rosa centifolia was administered orally to evaluate the immunostimulant activity against azathioprine induced immunosuppression. Evaluation was done by measuring the changes in hematological and enzymatic parameters. Results of all parameters exhibited immunostimulatory activity in Rosa centifolia.

Keywords

Rosa centifolia, Azathioprine, Hematological Changes, AST, ALT, Vitamin C.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Dash.S, Nath. L.K, Bhise.S; Kar. P, Bhattacharya.S. 2006. Stimulation of immune function activity by the alcoholic ischolar_main extract of Heracleum nepalense D. Don, Indian Journal of pharmacy. 38 (5); 336 – 340.

  • Fimmel; Zouboulis CC .2005 . Influence of physiological androgen levels on wound healing and immune status in men, Aging Male. 8; 166-174.

  • Janeway Jr. CA Travers. P.1994. Immunobiology. The immune system in health and disease, 23-24.

  • Mossman T.R, Coffman R.L. 1989.Th1 and Th2 cells, different pattern of lymphokine secretion lead to different functional properties, Annu Rev Immunol.,7; 145.

  • Reitman, S., Frankel, S. 1934. A colorimetric method for the determination of serum glutamic oxloacetate acid and glutamic pyruvate transaminases. Am. J., 31; 56-63.

  • Roe, J.H. and Kuether, C.A. 1943. The determination of ascorbic acid in whole blood and urine through the 2, 4-dinitrophenylhydrazine derivative of dehydroascorbic acid. J. Biol. Chem., 11: 145-164.

  • Sembulingam, Prema Sembulingam. 2006. Essentials of medical physiology, 83-128.


Abstract Views: 260

PDF Views: 2




  • Immunostimulatory Activity of Rosa centifolia in Azathioprine Induced Rats

Abstract Views: 260  |  PDF Views: 2

Authors

K. Akilandeswari
PG and Research Department of Biochemistry, S.T.E.T. Women's College, Sundarakkottai, Mannargudi -614001, Tamil Nadu, India
R. Anuradha
PG and Research Department of Biochemistry, S.T.E.T. Women's College, Sundarakkottai, Mannargudi -614001, Tamil Nadu, India

Abstract


The ethyl acetate extract of Rosa centifolia was administered orally to evaluate the immunostimulant activity against azathioprine induced immunosuppression. Evaluation was done by measuring the changes in hematological and enzymatic parameters. Results of all parameters exhibited immunostimulatory activity in Rosa centifolia.

Keywords


Rosa centifolia, Azathioprine, Hematological Changes, AST, ALT, Vitamin C.

References