Research Journal of Pharmacology and Pharmacodynamics

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Evaluation of Immunomodulatory Activity of Aqueous Extract of the Bulb of Allium sativam in Wistar Rats


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1 School of Pharmacy, CEC, Bilaspur - 495009, Chhattisgarh, India
     

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There is no effective drug for treatment of certain infections like AIDS, hepatitis, and other viral infections. For other infections the drug (mainly antibiotics) being used are becoming ineffective due to development of microbial resistance, necessitating the search for newer drugs. Any such new drug will be available only at an exorbitant cost due to the product patent norms under WTO agreement. This work is to prove the immunomodulatory property of Allium sativam in wistar rats by studying the Delayed Type Hypersensitivity (DTH), Humoral Antibody titre (HA), Total Leukocyte Count (TLC), and Differential Leukocyte Count (DLC) In The Aqueous Extract of Allium sativam. bulbs. The effect of this extract were comparable to the standards drug Levamisole all the data represents the Immunostimulatory activity of aqueous extract of the bulb of Allium sativam.
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  • Evaluation of Immunomodulatory Activity of Aqueous Extract of the Bulb of Allium sativam in Wistar Rats

Abstract Views: 249  |  PDF Views: 2

Authors

M. P. Singh
School of Pharmacy, CEC, Bilaspur - 495009, Chhattisgarh, India
R. Jaiswal
School of Pharmacy, CEC, Bilaspur - 495009, Chhattisgarh, India
S. Mandal
School of Pharmacy, CEC, Bilaspur - 495009, Chhattisgarh, India

Abstract


There is no effective drug for treatment of certain infections like AIDS, hepatitis, and other viral infections. For other infections the drug (mainly antibiotics) being used are becoming ineffective due to development of microbial resistance, necessitating the search for newer drugs. Any such new drug will be available only at an exorbitant cost due to the product patent norms under WTO agreement. This work is to prove the immunomodulatory property of Allium sativam in wistar rats by studying the Delayed Type Hypersensitivity (DTH), Humoral Antibody titre (HA), Total Leukocyte Count (TLC), and Differential Leukocyte Count (DLC) In The Aqueous Extract of Allium sativam. bulbs. The effect of this extract were comparable to the standards drug Levamisole all the data represents the Immunostimulatory activity of aqueous extract of the bulb of Allium sativam.

References