Research Journal of Pharmacology and Pharmacodynamics

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Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts


Affiliations
1 Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur- 416 013 (M.S.), India
2 Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, M. S., India
     

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Different extracts of Memecylon umbellatum Burm ischolar_main were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone ischolar_main extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities.

Keywords

Memecylon umbellatum, Anthelmintic, Anti-Insect, Pheretima posthuma, Tribolium castaneum.
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  • Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts

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Authors

S. G. Killedar
Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur- 416 013 (M.S.), India
H. N. More
Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, M. S., India

Abstract


Different extracts of Memecylon umbellatum Burm ischolar_main were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone ischolar_main extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities.

Keywords


Memecylon umbellatum, Anthelmintic, Anti-Insect, Pheretima posthuma, Tribolium castaneum.

References