Research Journal of Pharmacology and Pharmacodynamics

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Serous Fat Atrophy of Marrow: A Case Report


Affiliations
1 Department of Pathology, S.S. Medical College and Asso. S. G.M. Hospital Rewa (M.P.), India
2 Department of Pathology, S.S. Medical College and Asso. S.G.M. Hospital Rewa (M.P.), India
3 Department of Pediatrics, S.S. Medical College and Asso. S.G.M. Hospital Rewa (M.P.), India
4 Department of Pathology, S.S. Medical College and Asso. S.G.M. Hospital Rewa (M.P.), India
     

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Serous fat atrophy or gelatenous transformation of marrow (GMT) is a rare disorder of unknown pathogenesis characterized by cell atrophy, focal loss of haematopoietic cells and deposition of extra cellular material. This also has been termed as "Starvation Marrow". It is reversible with resolution of nutritional problem. It is an epiphenomenon associated with extreme malnutrition and weight loss. Its etiology is age related. It may be found in Kwashiorkar, anorexia nervosa, AIDS, cachexia, carcinoma, lymphoma, marrow damage caused by toxin, radiation or chemotherapy, it is sometimes seen early in course of aplastic anemia when it's probably indicate recent or ongoing marrow damage.

Keywords

Atrophy, Extra Cellular Material, Bone Marrow, Kwashiorkar, AIDS
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  • Serous Fat Atrophy of Marrow: A Case Report

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Authors

U. R. Singh
Department of Pathology, S.S. Medical College and Asso. S. G.M. Hospital Rewa (M.P.), India
S. K. Sutrakar
Department of Pathology, S.S. Medical College and Asso. S.G.M. Hospital Rewa (M.P.), India
P. C. Kol
Department of Pathology, S.S. Medical College and Asso. S. G.M. Hospital Rewa (M.P.), India
Sunil Rao
Department of Pediatrics, S.S. Medical College and Asso. S.G.M. Hospital Rewa (M.P.), India
Ravishanker Shrivastava
Department of Pathology, S.S. Medical College and Asso. S.G.M. Hospital Rewa (M.P.), India

Abstract


Serous fat atrophy or gelatenous transformation of marrow (GMT) is a rare disorder of unknown pathogenesis characterized by cell atrophy, focal loss of haematopoietic cells and deposition of extra cellular material. This also has been termed as "Starvation Marrow". It is reversible with resolution of nutritional problem. It is an epiphenomenon associated with extreme malnutrition and weight loss. Its etiology is age related. It may be found in Kwashiorkar, anorexia nervosa, AIDS, cachexia, carcinoma, lymphoma, marrow damage caused by toxin, radiation or chemotherapy, it is sometimes seen early in course of aplastic anemia when it's probably indicate recent or ongoing marrow damage.

Keywords


Atrophy, Extra Cellular Material, Bone Marrow, Kwashiorkar, AIDS

References