Research Journal of Pharmacognosy and Phytochemistry

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Evaluation of Suspending Properties of Mucilage of Linnum usitatisimum Linn. Seeds


Affiliations
1 Department of Pharmacognosy, MES College of Pharmacy, Sonai, 414105, Tal. Newasa, Dist. Ahmednagar (M.S.), India
2 Department of Pharmaceutical Sci., RTM Nagpur University, Nagpur (M.S.), 440010, India
3 P.W. Colleges of Pharmacy, Yavatmal (M.S.), 445001, India
     

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The purpose of this study is to search for a natural excipient that can be used as alternative in the formulation of pharmaceutical suspensions. Present study was carried out to evaluate suspending properties of mucilage of seeds Linnum usitatisimum Lin. with those of tragacanth and Acacia at concentration range of 1.0-4.0% w/v in calcium carbonate suspension. Evaluation parameters like sedimentation profile, redispersibility, and pH were compared with calcium carbonate (2.0% w/v) suspension prepared by using acacia and tragacanth gum as standard suspending agent. Suspension prepared with linseed mucilage was found a superior suspending agent than acacia and comparable with tragacanth. Linseed mucilage can be used as an effective alternative in the formulation of pharmaceutical suspensions.

Keywords

Suspending Agent, Linnum usitatisimum, Flax Seed, Mucilage.
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  • Evaluation of Suspending Properties of Mucilage of Linnum usitatisimum Linn. Seeds

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Authors

C. D. Khadse
Department of Pharmacognosy, MES College of Pharmacy, Sonai, 414105, Tal. Newasa, Dist. Ahmednagar (M.S.), India
R. B. Kakade
Department of Pharmaceutical Sci., RTM Nagpur University, Nagpur (M.S.), 440010, India
V. K. Deshmukh
Department of Pharmacognosy, MES College of Pharmacy, Sonai, 414105, Tal. Newasa, Dist. Ahmednagar (M.S.), India
D. S. Mohale
P.W. Colleges of Pharmacy, Yavatmal (M.S.), 445001, India

Abstract


The purpose of this study is to search for a natural excipient that can be used as alternative in the formulation of pharmaceutical suspensions. Present study was carried out to evaluate suspending properties of mucilage of seeds Linnum usitatisimum Lin. with those of tragacanth and Acacia at concentration range of 1.0-4.0% w/v in calcium carbonate suspension. Evaluation parameters like sedimentation profile, redispersibility, and pH were compared with calcium carbonate (2.0% w/v) suspension prepared by using acacia and tragacanth gum as standard suspending agent. Suspension prepared with linseed mucilage was found a superior suspending agent than acacia and comparable with tragacanth. Linseed mucilage can be used as an effective alternative in the formulation of pharmaceutical suspensions.

Keywords


Suspending Agent, Linnum usitatisimum, Flax Seed, Mucilage.