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Analgesic Activity of the Isolated Constituent Syzygium cuminii (L) skeel


Affiliations
1 Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
2 Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
     

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The present study was carried out to investigate the analgesic activity of the prepared formulation 50mg/kg and 200mg/kg body weight in the form of gel on albino rats by Tail immersion method. The different dose level of prepared gel was applied to the rat according to the body weight to the tail which is marked at 5cm and was subjected to analgesic activity. The significance analgesic activity is observed after 1/2 hr of the application which was compared with standard dichlofenac gel, the activity decreased after 2 hr of the application. The gel was prepared from the isolated constituents of syzygium cuminii (L) skeel ischolar_main extract. The aim of the work is to prepare such a formulation which is having natural analgesic activity. The expected result from the formulation was obtained for first time. The further work is going on in our laboratory.


Keywords

Analgesic, Dichlofenac Gel, Formulation, Constituents.
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  • Analgesic Activity of the Isolated Constituent Syzygium cuminii (L) skeel

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Authors

F. Nikhat
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
D. Satyanarayana
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
D. K. Suresh
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
M. G. Purohit
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
H. Raza
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India
S. M. Hamza
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, India

Abstract


The present study was carried out to investigate the analgesic activity of the prepared formulation 50mg/kg and 200mg/kg body weight in the form of gel on albino rats by Tail immersion method. The different dose level of prepared gel was applied to the rat according to the body weight to the tail which is marked at 5cm and was subjected to analgesic activity. The significance analgesic activity is observed after 1/2 hr of the application which was compared with standard dichlofenac gel, the activity decreased after 2 hr of the application. The gel was prepared from the isolated constituents of syzygium cuminii (L) skeel ischolar_main extract. The aim of the work is to prepare such a formulation which is having natural analgesic activity. The expected result from the formulation was obtained for first time. The further work is going on in our laboratory.


Keywords


Analgesic, Dichlofenac Gel, Formulation, Constituents.