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Modeling Techniques – Novel Approach to Skin Permeability Measurement


Affiliations
1 Pharmaceutics and Dosage Form Development, Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
2 Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
3 Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
     

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The stratum corneum, possess a formidable challenge to formulators of drug delivery systems. In this review, various aspects of penetration through the stratum corneum have been highlighted with use of new mathematical models. These models are useful for enhancement strategies of drugs through dermal penetration and are also use in predicting pharmacological and toxicological point of view. These techniques are used to control the penetration rate through stratum corneum.

Keywords

Stratum Corneum, Mathematical Models, Pharmacological, Toxicological.
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  • Modeling Techniques – Novel Approach to Skin Permeability Measurement

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Authors

Mohit Soni
Pharmaceutics and Dosage Form Development, Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
Daisy Sharma
Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
Tejvir Kaur
Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
Sandeep Kumar
Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India
G. D. Gupta
Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, India

Abstract


The stratum corneum, possess a formidable challenge to formulators of drug delivery systems. In this review, various aspects of penetration through the stratum corneum have been highlighted with use of new mathematical models. These models are useful for enhancement strategies of drugs through dermal penetration and are also use in predicting pharmacological and toxicological point of view. These techniques are used to control the penetration rate through stratum corneum.

Keywords


Stratum Corneum, Mathematical Models, Pharmacological, Toxicological.