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Haematological Study on the Fungicide Ziram Induced Acute, Subacute and Subchronic Toxicity in Broiler Chickens


Affiliations
1 Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
 

The present work was conducted to elucidate the haematological changes in broiler chickens after Ziram intoxication. For this study, 150 apparently healthy broiler chicks were reared up to 2 weeks of age and randomly allocated to four groups, i.e. acute (N=10), sub-acute (N=20), sub-chronic (N=90) and control (N=30). Toxicity was induced following a single oral dose of Ziram @ 100mg/kg body weight for acute intoxication; 5 mg/kg body weight per day for 20 days in case of sub-acute group and 1mg/kg body weight per day for the study period of 90 days in case of sub-chronic intoxication. At the end of the experimental period the investigations revealed significant decrease in haemoglobin concentration, packed cell volume, total erythrocyte count and leucocytosis with heterophilia leading to clinical anaemia.

Keywords

Broiler Chickens, Ziram Fungicide, Toxicity, Haematology.
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  • Haematological Study on the Fungicide Ziram Induced Acute, Subacute and Subchronic Toxicity in Broiler Chickens

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Authors

Majid Shafi
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
Shayaib Ahmad Kamil
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
Masood Saleem Mir
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
Mohammed Maqbool Darzi
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
Abdul Shakoor Bhat
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
Showkat Shah
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India
Khadim Hussain Dar
Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, India

Abstract


The present work was conducted to elucidate the haematological changes in broiler chickens after Ziram intoxication. For this study, 150 apparently healthy broiler chicks were reared up to 2 weeks of age and randomly allocated to four groups, i.e. acute (N=10), sub-acute (N=20), sub-chronic (N=90) and control (N=30). Toxicity was induced following a single oral dose of Ziram @ 100mg/kg body weight for acute intoxication; 5 mg/kg body weight per day for 20 days in case of sub-acute group and 1mg/kg body weight per day for the study period of 90 days in case of sub-chronic intoxication. At the end of the experimental period the investigations revealed significant decrease in haemoglobin concentration, packed cell volume, total erythrocyte count and leucocytosis with heterophilia leading to clinical anaemia.

Keywords


Broiler Chickens, Ziram Fungicide, Toxicity, Haematology.

References