Journal of Pharmaceutical Research

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A Review:Solid Dispersion, a Technique of Solubility Enhancement


Affiliations
1 Krupanidhi College of Pharmacy, Chikkabellandur Village, Carmelaram Post, Varthur Hobli, Bangalore - 560035, India
 

Purpose: The aim of the study was to explore the necessity, advantages and different techniques of solid dispersion for enhancing solubility of poorly soluble drugs.

Approach: Different types of solid dispersion have been explained briefly along with the various techniques of solid dispersion in detail.

Findings: Solid dispersions of poorly soluble drugs have been found to give positive results in enhancing its solubility and dissolution characters.

Conclusion: Solid dispersion techniques improve solubility and bioavailability of poorly soluble drugs. Solid dispersions can be incorporated into various dosage forms with wide range of applicability.


Keywords

Solid Dispersion Techniques, Solubility, Advantages, Disadvantages, Carriers.
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Abstract Views: 332

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  • A Review:Solid Dispersion, a Technique of Solubility Enhancement

Abstract Views: 332  |  PDF Views: 102

Authors

Sangam Shrestha
Krupanidhi College of Pharmacy, Chikkabellandur Village, Carmelaram Post, Varthur Hobli, Bangalore - 560035, India
Preethi Sudheer
Krupanidhi College of Pharmacy, Chikkabellandur Village, Carmelaram Post, Varthur Hobli, Bangalore - 560035, India
Bharani S. Sogali
Krupanidhi College of Pharmacy, Chikkabellandur Village, Carmelaram Post, Varthur Hobli, Bangalore - 560035, India
Deborose Soans
Krupanidhi College of Pharmacy, Chikkabellandur Village, Carmelaram Post, Varthur Hobli, Bangalore - 560035, India

Abstract


Purpose: The aim of the study was to explore the necessity, advantages and different techniques of solid dispersion for enhancing solubility of poorly soluble drugs.

Approach: Different types of solid dispersion have been explained briefly along with the various techniques of solid dispersion in detail.

Findings: Solid dispersions of poorly soluble drugs have been found to give positive results in enhancing its solubility and dissolution characters.

Conclusion: Solid dispersion techniques improve solubility and bioavailability of poorly soluble drugs. Solid dispersions can be incorporated into various dosage forms with wide range of applicability.


Keywords


Solid Dispersion Techniques, Solubility, Advantages, Disadvantages, Carriers.

References