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The macroscopic and microscopic characters of the leaf of Calotropis gigantea R. Br. ex Ait. which is used in the indigenous system of medicine are described. Three layers of closely packed palisade cells, multicellular thin walled trichomes and presence of half stomata in the lower epidermis besides the rubiaceous type of stomata, absence of tannin and presence of fats and oils are the chief diagnostic characters.
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