Journal of Ecophysiology and Occupational Health

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Chemical Signatures of New Pesticides in the Bovine and Caprine Milk Samples Collected from Western Uttar Pradesh (India)


Affiliations
1 Department of Toxicology, Chaudhary Charan Singh University, Meerut– 250004, Uttar Pradesh, India
 

Raw buffalo, cow and goat milk collected from different locations of Northern India has been analyzed for suspected pesticides viz. azimsulfuron, cypermethrin, thiabendazole, crotonolactone, fluoxastrobin, aldicarb and carbofuran. Buffalo milk tested positive for azimsulfuron (4.51 ng/ml), cypermethrin (7.21 ng/ml) and thiabendazole (4.57 ng/ml). Cow’s milk did not show the presence of cypermethrin and thiabendazole, however, azimsulfuron (0.86 ng/ml), crotonolactone (4.73 ng/ml) and fluoxastrobin (0.54 ng/ml) were determined. Milk of the goats registered the presence of carbafuron (7.69 ng/ ml), fluoxastrobin (5.41 ng/ml) and azimsulfuron (5.28 ng/ml). Since all the milching cattle are herbivorous, these pesticides entered animal through food chain. The consumption of milk containing these pesticides even in traces may be hazardous to human population of Northern India. Concurrent presence of these pesticides may be more hazardous due to their synergistic manifestations. New synthetic molecules like azimsulfuron, fluoxastrobin and crotonolactone may pose severe public health problems.


Keywords

Carbamates, Milk, Organochlorines, Organophosphates, Pyrethroids and Public Health
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  • Davies JF, Freed VH, Whittemore FW. An Agro Medical Approach to Pesticide management, University of Miami School of Medicine, Coral Gables; 1986.

  • FAO [Internet]. 2012. Available from: http://www.fao.org/fileadmin/templates/est/COMM_MARKETS_MONIT ORING/Dairy/Documents/FO_May_2015- Dairy.pdf

  • Dakeishi M, Murata K, Grandjean P. Long-term consequences of arsenic poisoning during infancy due to contaminated milk powder. Environmental Health. 2006; 5:31. https://doi.org/10.1186/1476-069X-5-31.

  • PMid:17076881. PMCid:PMC1635412

  • Bernard A, Gilbert H. The Belgian PCB/Dioxin incident: Analysis of the food chain contamination and health risk evaluation. Environmental Research. 2002; 88:1–18. https://doi.org/10.1006/enrs.2001.4274. PMid:11896663

  • Ruijia Y, Huang W, Zhang L. Milk adulteration with melamine in China: Crisis and response. Quality Assurance and Safety of Crops & Foods. 2009; 1:111– 16. https://doi.org/10.1111/j.1757-837X.2009.00018.x

  • Shahzadi N, Imran M, Sarwar M, Hashmi AB, Wasim M. Identification of pesticides residue in different samples of milk. Journal of Agroalimentary Processes and Technologies. 2013; 19:167–72.

  • Ashnagar A, Gharib NN, Cheraghi FM. Determi nation of Organochlorine pesticide residues in cow's milk marketed in Ahwaz city of Iran. International Journal of PharmTech Research. 2009; 1:247–51.

  • Shaker EM, Elsharkawy EE. Organochlorine and organophosphorus pesticide residues in raw buffalo milk from agroindustrial areas in Assiut,Egypt. Environmental Toxicology and Pharmacology. 2015; 39:433–40. https://doi.org/10.1016/j.etap.20 14.12.005. PMid:25575291

  • Witczak A, Pohorylo A, Malek AM. Assessment of health risk from organochlorines xenobiotics in goat milk for consumers in Poland. Chemosphere. 2016; 148:395–402.https://doi.org/10.1016/j.chemo sphere.2016.01.025. PMid:26829307

  • Nath A, Vendan SE, Priyanka, Singh JK, Singh CK, Kumar S. Carcinogenic pesticides residue detection in cow's milk and water samples from Patna, India. Current Trends in Biotechnology and Chemical Research. 2013; 3:1–8.

  • Barman RM, Mishra BK, Barman A. OCP residues analysis in cow milk of Dhanbad city, Jharkhand, India. International Journal of Applied and Pure Science and Agriculture. 2016; 2:1–11.

  • Nag SK, Raikwar MK. Organochlorine pesticide residues in Bovine milk. Bulletin of Environmental Contamination and Toxicology. 2008; 80:5–9. https://doi.org/10.1007/s00128-007-9276-6. PMid:17940716

  • Kaushik CP, Sharma HR, Gulati D, Kaushik A. Changing patterns of organochlorines pesticide residues in raw bovine milk from Haryana, India. Environmental Monitoring and Assessment. 1999; 182:467–75. https://doi.org/10.1007/s10661-0111890-4. PMid:21331758

  • John PJ, Bakore N, Bhatnager P. Assessment of Organochlorine Pesticide Residue Levels in Dairy Milk and Buffalo Milk from Jaipur City, Rajasthan, India. Environment International. 2001; 26:231–6.

  • https://doi.org/10.1016/S0160-4120(00)00111-2

  • FAO/WHO. Joint FAO/WHO Food Standards Programme-Codex Alimentarius Commission-Codex Alimentarius- Volume II. Pesticide Residues in Food. Food Agriculture Organization/World Health Organization, Rome; 1993.

  • Lehotay SJ. Quick, easy, cheap, effective, rugged and safe approach for determining pesticide residues. Methods in Biotechnology. Vol.19- Pesticide Protocols. Totowa, NJ: Humana Press Inc.; 2006. https://doi.org/10.1385/159259-929-X:239

  • Kampire E, Kiremire BT, Nyanzi SA, Kishimba M. Organochlorine pesticide in fresh and pasteurized cow's milk from Kampala markets. Chemosphere. 2011; 84:923– 7. https://doi.org/10.1016/j.chemosphere.2011.06.011. PMid:21737114

  • Duarte-Davidson R, Jones KC. Screening the environmental fate of organic contaminants in sewage sludges applied to agricultural soils: The potential for trans fer to plants and grazing animals. Science of the Total Environment.1996; 185:59–70.https://doi.org/10.1016/0048-9697(96)05042-5

  • Fries GF. Ingestion of sludge applied organic chemicals by animals. Science of the Total Environment. 1996; 185:93– 108. https://doi.org/10.1016/0048-9697(96)05045-0 20. Gupta PK. Pesticide exposure- Indian scene. Toxico logy. 2004; 198:83–90. https://doi.org/10.1016/j.tox.200 4.01.021. PMid:15138033

  • USFDA (U.S. Food and Drug Administration) [Inter net].2014. Pesticides residue monitoring program fiscal year 2014 pesticide report. Available from: http://www.fda.gov/food/foodborneillnesscontaminants/pesticides/default.htm

  • Bluthgen A. Contamination of milk from feed. Bulletin of the International Dairy Federation. 2000; 356:43–7.

  • Heck MC, Santos J, Bogusz S, Costabeber I, Emanuelli T. Estimation of children exposure to organochlorine compounds through milk in Rio Grande do Sul, Brazil. Food Chemistry. 2007; 102:288–94. https://doi.org/10.1016/j.foodchem.2006.05.019

  • Rychen G, Jurjanz S, Fournier A, Toussaint H, Feidt C. Exposure of ruminants to persistent organic pollutants and potential of decontamination. Environ. Sci. pollut. Res. 2014; 21:6440–7. https://doi.org/10.1007/s11356013-1882-8. PMid:23764985

  • La Rocca C, Montovani A. From environment to food: The case of PCB. Ann Ist Super Sanita. 2006; 42(4):410–16.

  • Durand B, Dufour B, Fraisse D, Defour S, Duhem K, Le-Barillec K. Levels of PCDDs, PCDFs and dioxinlike PCBs in raw cow's milk collected in France in 2006. Chemosphere. 2008; 70:689–93. https://doi.org/10.1016/j.chemosphere.2007.06.057. PMid:17707881

  • Fagnani R, Beloti V, Battaglini AP, Dunga KS, Tamanani R. Organophosphorus and carbamates residues in milk and feedstuff supplied to dairy cattle. Pesquisa Veterinaria Brasileira. 2011; 31:598–602. https://doi.org/10.1590/S0100-736X2011000700009

  • USEPA (US Environmental Protection Agency) [Inter net]. 2005 Jan 24. Fluoxastrobin human health risk assessment. Document ID: EPA-HQ-OPP-2003-0129. Available from:http://www.epa.gov/opprd001/factsheets/

  • Currance PL, Clements B, Bronstein AC. Emergency care for hazardous materials exposure. 3rd ed. Louis, MO, Elsevier Mosby; 2005. p. 298–390.

  • Darnerud PO, Atuma S, Aule M, Bjerelius R, Glynn A, Grawe KP, Becker W. Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data. Food Chem. Toxicol. 2006; 44:1597–606. https://doi.org/10.1016/j.fct.2006.03.011. PMid:16730400

  • Polder A, Savinowa TN, Tkachev A, Loken KB, Odland JO, Skarre JU. Levels and pattern of persistent organic pollutants (POPs) in selected food items from northwest Russia (1998-2002) and implications for dietary exposure. Sci. Total Environ. 2010; 3:5352–61. https://doi.org/10.1016/j.scitotenv.2010.07.036. PMid:20719362

  • Schettino B, Gutierrez R, Ortiz R, Vega S, Uraban G, Ramirez A. Residues of legacy organochlorine contam inants in the milk of Alpine and Saanen goats from the central region of Mexico. Bulletin of Environmental Contamination and Toxicology. 2013; 91:154–9. https://doi.org/10.1007/s00128-013-1005-8. PMid:23689930

  • Kan CA, Meijer GAL. The risk of contamination of food with toxic substances present in animal feed. Animal Feed Science and Technology. 2007; 133:84–108. https://doi.org/10.1016/j.anifeedsci.2006.08.005

  • Risher JF, Franklin LM, Jerry FS. The toxicological effects of the carbamate insecticide aldicarb in mammals: A Re view. Environmental Health Perspectives. 1987; 72:267– 81. https://doi.org/10.1289/ehp.8772267. PMid:3304999 PMCid:PMC1474664


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  • Chemical Signatures of New Pesticides in the Bovine and Caprine Milk Samples Collected from Western Uttar Pradesh (India)

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Authors

Suresh V. S. Rana
Department of Toxicology, Chaudhary Charan Singh University, Meerut– 250004, Uttar Pradesh, India
Yeshvandra Verma
Department of Toxicology, Chaudhary Charan Singh University, Meerut– 250004, Uttar Pradesh, India
Uday Veer Rathi
Department of Toxicology, Chaudhary Charan Singh University, Meerut– 250004, Uttar Pradesh, India
Lalit Mohan Vashistha
Department of Toxicology, Chaudhary Charan Singh University, Meerut– 250004, Uttar Pradesh, India

Abstract


Raw buffalo, cow and goat milk collected from different locations of Northern India has been analyzed for suspected pesticides viz. azimsulfuron, cypermethrin, thiabendazole, crotonolactone, fluoxastrobin, aldicarb and carbofuran. Buffalo milk tested positive for azimsulfuron (4.51 ng/ml), cypermethrin (7.21 ng/ml) and thiabendazole (4.57 ng/ml). Cow’s milk did not show the presence of cypermethrin and thiabendazole, however, azimsulfuron (0.86 ng/ml), crotonolactone (4.73 ng/ml) and fluoxastrobin (0.54 ng/ml) were determined. Milk of the goats registered the presence of carbafuron (7.69 ng/ ml), fluoxastrobin (5.41 ng/ml) and azimsulfuron (5.28 ng/ml). Since all the milching cattle are herbivorous, these pesticides entered animal through food chain. The consumption of milk containing these pesticides even in traces may be hazardous to human population of Northern India. Concurrent presence of these pesticides may be more hazardous due to their synergistic manifestations. New synthetic molecules like azimsulfuron, fluoxastrobin and crotonolactone may pose severe public health problems.


Keywords


Carbamates, Milk, Organochlorines, Organophosphates, Pyrethroids and Public Health

References





DOI: https://doi.org/10.18311/jeoh%2F2021%2F26248