International Journal of Chemistry and Chemical Engineering

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Effect of Celastrus Paniculatus on Learning, Memory and Serum Biochemistry of Aging Albino Rats


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1 Department of Chemistry, Singhania University, Pacheri Bari, Distt. Jhunjhunu, Rajasthan-333515, India
     

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Ethanol extract of Celastrus paniculatus was administered at the rate of 2g/kg body weight orally 16 days before trial experiment in male Wister albino rats of 3, 12 and 20 months old animals. They were studied for learning and memory process as well as for any change in the serum biochemistry. All animals were trained on Y-maze. Each animal received a daily session of 10 trials for 5 days i.e. a maximum of 50 trials. Increase in response of 5th session as compared to 1st session was taken as criteria of learning and memory. There was a significant increase in learning and memory in the treated group with respect to its control. Results show that Celastrus paniculatus preferentially affects learning and recall of memory and also regulate the serum biochemistry.

Keywords

Learning, Memory, Serum, Y-Maze
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  • Effect of Celastrus Paniculatus on Learning, Memory and Serum Biochemistry of Aging Albino Rats

Abstract Views: 616  |  PDF Views: 2

Authors

Mohsen Younus
Department of Chemistry, Singhania University, Pacheri Bari, Distt. Jhunjhunu, Rajasthan-333515, India
Madhu Agarwal
Department of Chemistry, Singhania University, Pacheri Bari, Distt. Jhunjhunu, Rajasthan-333515, India

Abstract


Ethanol extract of Celastrus paniculatus was administered at the rate of 2g/kg body weight orally 16 days before trial experiment in male Wister albino rats of 3, 12 and 20 months old animals. They were studied for learning and memory process as well as for any change in the serum biochemistry. All animals were trained on Y-maze. Each animal received a daily session of 10 trials for 5 days i.e. a maximum of 50 trials. Increase in response of 5th session as compared to 1st session was taken as criteria of learning and memory. There was a significant increase in learning and memory in the treated group with respect to its control. Results show that Celastrus paniculatus preferentially affects learning and recall of memory and also regulate the serum biochemistry.

Keywords


Learning, Memory, Serum, Y-Maze

References