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Asthma – Current Trends and Management Perspectives


Affiliations
1 Assistant Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
2 Associate Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
3 Professor and Head, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
4 Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
5 Professor and Head, Department of Internal Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
     

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Bronchial asthmais a chronic inflammatory disorder of the airways in which several cells and cellular elements play an important role, the hallmark of which is airway hyperresponsiveness, or an exaggerated response (bronchoconstriction) on exposure to certain triggers such as allergens and/or respiratory infections and others. The airway inflammation and obstruction are usually reversible but manifest clinically as acute episodes of wheezing, breathlessness, cough, or chest tightness, that occur particularly at night or early in the morning. Exacerbations and comorbidities affect disease severity as well as impact treatment success in many patients. Therapies are directed toward controlling airway inflammation and relieving airway obstruction.

Keywords

Asthma, BA, Airway Inflammation, Airway Hyperresponsiveness, EIA, ICS.
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  • Asthma – Current Trends and Management Perspectives

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Authors

Nikhil Sarangdhar
Assistant Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
Priya Deshpande
Assistant Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
Shahid Patel
Associate Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
Girija Nair
Professor and Head, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
Abhay Uppe
Professor, Department of Pulmonary Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India
Nivedita Moulick
Professor and Head, Department of Internal Medicine, D. Y. Patil University School of Medicine, Navi Mumbai, India

Abstract


Bronchial asthmais a chronic inflammatory disorder of the airways in which several cells and cellular elements play an important role, the hallmark of which is airway hyperresponsiveness, or an exaggerated response (bronchoconstriction) on exposure to certain triggers such as allergens and/or respiratory infections and others. The airway inflammation and obstruction are usually reversible but manifest clinically as acute episodes of wheezing, breathlessness, cough, or chest tightness, that occur particularly at night or early in the morning. Exacerbations and comorbidities affect disease severity as well as impact treatment success in many patients. Therapies are directed toward controlling airway inflammation and relieving airway obstruction.

Keywords


Asthma, BA, Airway Inflammation, Airway Hyperresponsiveness, EIA, ICS.

References