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Hyperpyrexia in a Patient with COVID-19


Affiliations
1 Consultant Emergency Medicine, Paras Hospital, Gurugram, India
2 Clinical Associate, Department of Emergency Medicine, Sir HN Hospital, Mumbai, India
3 Consultant Pulmonary Medicine, Sir HN Hospital, Mumbai, India
 

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The COVID- 19 pandemic has been a significant burden on global health care systems leading to over 5 million deaths worldwide and notable increase in morbidity. The second wave of the pandemic in India posed new challenges in the form of increased cases of severe disease, high case loads, younger patients and atypical presentations. It is critical to keep an eye on these unusual cases in order to increase the awareness about varied presentation of this relatively new disease.


Keywords

Hyperpyrexia, COVID 19, hypothalamus
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  • Hall JE, Guyton AC. Guyton and Hall textbook of medical physiology. Philadelphia, PA: Saunders Elsevier; 2011.

  • Osilla EV, Marsidi JL, Sharma S. Physiology, Temperature Regulation. 2021 May 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan. PMID: 29939615.

  • Walter EJ, Hanna-Jumma S, Carraretto M, Forni L. The pathophysiological basis and consequences of fever. Crit Care. 2016 Jul 14;20(1):200.

  • Hussein O, Torbey M. Hyperpyrexia as the presenting symptom of intracranial hypotension. Neurocrit Care. 2017;28(3):395-399.

  • Atha WF. Heat-related illness. Emerg Med Clin North Am. 2013 Nov;31(4):1097-108.

  • Thompson HJ, Tkacs NC, Saatman KE, Raghupathi R, McIntoshb TK. Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiology of Disease.2003 April;12(3):163–173. doi: http://doi:10.1016/S09699961(02)00030-X

  • Han H, Ma Q, Li C, Liu R, Zhao L, Wang W, Zhang P, Liu X, Gao G, Liu F, Jiang Y. Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors. Emerg Microbes Infect. 2020;9(1):1123-1130.22221751.2020.1770129. doi: https://doi.org/10.1080/

  • Qin C, Zhou L, Hu Z, Zhang S, Yang S, Tao Y, Xie C, Ma K, Shang K, Wang W, Tian DS. Dysregulation of immune response in patients with COVID-19 in Wuhan, China.Clin Infect Dis. 2020 Jul 28;71(15):762-8. doi: https://doi.org/10.1093/cid/ciaa248

  • Seoh JY, Khan M, Park SH, Park HK, Shin MH, Ha EH, Lee BE, Yoo K, Han HS, Oh S, Wi JH. Serum cytokine profiles in patients with Plasmodium vivax malaria: a comparison between those who presented with and without hyperpyrexia. Am J Trop Med Hyg. 2003;68(1):102-106.

  • Suwanwongse K, Shabarek N. Hyperpyrexia in patients with COVID-19. J Med Virol. 2020;92:2857–2862. doi: https://doi.org/10.1002/jmv.26154

  • Dinarello CA. Thermoregulation and the pathogenesis of fever. Infect Dis Clin North Am. 1996;10(2):433‐449. doi:https://doi.org/10.1016/s0891-5520(05)70306-8.


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  • Hyperpyrexia in a Patient with COVID-19

Abstract Views: 117  |  PDF Views: 77

Authors

Shweta Tyagi
Consultant Emergency Medicine, Paras Hospital, Gurugram, India
Gopal Chaturvedi
Clinical Associate, Department of Emergency Medicine, Sir HN Hospital, Mumbai, India
Rajesh Sharma
Consultant Pulmonary Medicine, Sir HN Hospital, Mumbai, India

Abstract


The COVID- 19 pandemic has been a significant burden on global health care systems leading to over 5 million deaths worldwide and notable increase in morbidity. The second wave of the pandemic in India posed new challenges in the form of increased cases of severe disease, high case loads, younger patients and atypical presentations. It is critical to keep an eye on these unusual cases in order to increase the awareness about varied presentation of this relatively new disease.


Keywords


Hyperpyrexia, COVID 19, hypothalamus

References