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Bilateral Glandular Odontogenic Cyst of the Maxilla: A Rare Case Report and Review of Literature


Affiliations
1 Dr BR Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India
2 IMS BHU, Varanasi, India
 

The glandular odontogenic cyst (GOC) is a recently recognized rare developmental odontogenic cyst having an aggressive behavior and accounts for 0.012 to 1.3% of all jaw cysts. In 1992, the World Health Organization recognized this cyst as glandular odontogenic cyst (GOC). Clinically, GOC usually presents as a painless, slow-growing swelling that tends to affect the anterior part of the jaws. Many authors have suggested that the cyst mainly occurs in 4th and 5th decades and presents as an expansion of jaws with or without pain or Paraesthesia. The dental professionals must be aware of the clinical significance of this lesion as the aggressive nature of the lesion has been reported and at least 25% to 55% recur following curettage. Hence the treatment of choice is excision rather than enucleation in order to obviate recurrence. Here, we report a case of bilateral GOC in the anterior region of the maxilla, in a 29-year-old male patient, which is very unusual as it is the first bilateral case to be reported in the literature.

Keywords

Glandular Odontogenic Cyst, Maxilla, Bilateral.
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  • Padayachee A, Van Wyk CW. Two cystic lesions with features of both the botryoid odontogenic cyst and the central mucoepidermoid tumour: sialoodontogenic cyst? J Oral Pathol 1987;16:499–504.
  • Gardner DG, Kessler HP, Morency R, Schaffner DL. The glandular odontogenic cyst: an apparent entity. J Oral Pathol 1988;17:359–366.
  • Kramer IRH, Pindborg JJ, Shear M. Histological typing of odontogenic tumors. 2nd ed. Berlin: Springer-Verlag; 1992.p.38.
  • Kaplan I, Anavi Y, Hirshberg A. Glandular odontogenic cyst: a challenge in diagnosis and treatment. Oral Dis 2008;14:575–81.
  • Krishnamurthy A, Sherlin HJ, Ramalingam K, Natesan A, Premkumar P, Ramani P, et al. Glandular Odontogenic Cyst: Report of Two Cases and Review of Literature. Head and Neck Pathol 2009;3:153–158.
  • Magnussson B, Goransson L, Odesjo B, Grondahl K, Hirsch JM. Glandular odontogenic cyst: report of seven cases. Dentomaxillofac Radiol 1997;26:26.
  • Ertas U. A large glandular odontogenic cyst of the mandible: report of a case. J Cont Den Pract 2003;1:1-3.
  • Rajendren R, Sivapathasundharam B Shafer, Hine, Levy's textbook of Oral Pathology. 5th ed. India: Elsevier; 2006.p.267-68.
  • Manor R, Anavi Y, Kaplan I, Calderon S. Radiological features of glandular odontogenic cyst. Dentomaxillofac Radiol 2003;32:73–9.
  • Barreto, Marco LD, DL Wagner HC, Gomez RS. Glandular odontogenic cyst: absence of PTCH gene mutation. J Oral Pathol Med 2001;30:125-8.
  • Tran PT, Cunningham CJ, Baughman RA. Glandular odontogenic cyst. J Endod 2004;30:182.
  • Noffke C, Raubenheimer EJ. The glandular odontogenic cyst: clinical and Radiological features; review of literature and report of nine cases. Dentomaxillofac Radiol 2002;31:333.
  • Binda JE, Kuepper R, Pulse C. Glandular odontogenic cyst: a case report and review of the literature. Col Dent Rev 1997;2:1.
  • Velez I. Glandular Odontogenic Cyst. Report of Two Cases and Review of the Literature. NYSDJ. January 2006;44-45.
  • Van Heerden WF, Raubenheimer EJ, Turner ML. Glandular odontogenic cyst. Head Neck 1992;14:316–320.
  • Kreidler JF, Raubenheimer EJ, Van Heerden WF. A retrospective analysis of 367 cystic lesions of the jaw—the Ulm experience. J Craniomaxillofac Surg 1993;21:339–341.
  • Manojlovic S, Grgurevic J, Knezevic G, Kruslin B. Glandular odontogenic cyst: a case report and clinicopathologic analysis of the relationship to central mucoepidermoid carcinoma. Head and Neck 1997;19:227–231.
  • Waldron CA, Koh ML. Central mucoepidermoid carcinoma of the jaws: report of four cases with analysis of the literature and discussion of the relationship to mucoepidermoid, sialodontogenic, and glandular odontogenic cysts. J Oral Maxillofac Surg 1990;48:871–877.
  • Altini M, Shear M. The lateral periodontal cyst: An update. J Oral Pathol Med 1992;21:245–250.
  • Shear M. Developmental odontogenic cysts. An update. J Oral Pathol Med 1994;23:1–11.
  • MacDonald -Jankowski DS. Glandular odontogenic cyst: systematic review. Dentomaxillofacial Radiology 2010;39(3):127-139.
  • Kaplan I, Gal G, Anavi Y, Manor R, Calderon S. Glandular odontogenic cyst: treatment and recurrence. J Oral Maxillofac Surg 2005;63:435–441.
  • Shen J, Fan M, Chen X, Wang S, Wang L, Li Y. Glandular odontogenic cyst in China: report of 12 cases and immunohistochemical study. J Oral Pathol Med 2006;35: 175–182.
  • Economopoulou P, Patrikiou A. Glandular odontogenic cyst of the maxilla: report of a case. J Oral Maxillofac Surg 1995;53(7):834–7.
  • Tosios K, Angelopaulou EK, Kapranos N. Immunohistochemical study of bcl-2 protein, ki67 antigen and p53 protein in epithelium of glandular odontogenic cysts and dentigenous cysts. J Oral Pathol Med 2000;29:139-44.
  • Cawson RA, Binnie WH, Speight PM, Barrett AW, Wright JM. Lucas's pathology of tumors of the oral tissues. 5th ed. London: Churchill Livingstone;1998.p.129-130.
  • Regezi JA. Odontogenic cysts, odontogenic tumors, fibrosseous and giant cell lesions of the jaws. Mod Pathol 2002;15:33.
  • Shear M, Pindborg JJ. Microscopic features of the lateral periodontal cyst. Scand J Dent Res 1975;83:103.
  • Gurol M, Burkes EJ Jr, Jacoway J. Botryoid odontogenic cyst. Analysis of 33 cases. J Periodontol 1995;66:1069.
  • De Soussa SO, Cabexas NT, De Oliveira PT, De Araujo VC. Glandular odontogenic cyst report of a case with cytokeratin expression. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83:478–83.
  • Kaplan I, Anavi Y, Manor R, Sulkes J, Calderon S. The use of molecularmarkers as an aid in the diagnosis of glandular odontogenic cyst. Oral Oncol 2005;41:895–902.
  • Pires FR, Chen SY, Perez DEC, Almedia OP, Kowalski LP. Cytokeratin expression in central mucoepidermoid carcinoma and glandular odontogenic cyst. Oral Oncol 2004;40:545–51.
  • Ficarra G, Chou L, Panzoni E. Glandular odontogenic cyst (sialo-odontogenic cyst). A case report. J Oral PatholMed 1990;19:331-3.
  • Ide F, Shimoyama T, Horie N. Glandular odontogenic cyst with hyaline bodies: an unusual dentigerous presentation. J Oral Pathol Med 1996;25:401-4.
  • Ramer M, Montazem A, Lane SL, Lumerman H. Glandular odontogenic cyst. Report of a case and review of the literature. Oral Surg Oral Med Oral Pathol 1997;84:54-7.
  • Nair RG, Varghese IV, Shameena PM, Sudha S. Glandular odontogenic cyst: Report of a case and review of literature. J Oral Maxillofac Pathol 2006;10:20-3.
  • Li TJ, Matthews JB. Quantification of PCNA cells within odontogenic jaw cyst epithelium. J Oral Pathol Med 1994;23:184-9

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  • Bilateral Glandular Odontogenic Cyst of the Maxilla: A Rare Case Report and Review of Literature

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Authors

Abhilasha Asthana
Dr BR Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India
Amit Kumar Singh
IMS BHU, Varanasi, India

Abstract


The glandular odontogenic cyst (GOC) is a recently recognized rare developmental odontogenic cyst having an aggressive behavior and accounts for 0.012 to 1.3% of all jaw cysts. In 1992, the World Health Organization recognized this cyst as glandular odontogenic cyst (GOC). Clinically, GOC usually presents as a painless, slow-growing swelling that tends to affect the anterior part of the jaws. Many authors have suggested that the cyst mainly occurs in 4th and 5th decades and presents as an expansion of jaws with or without pain or Paraesthesia. The dental professionals must be aware of the clinical significance of this lesion as the aggressive nature of the lesion has been reported and at least 25% to 55% recur following curettage. Hence the treatment of choice is excision rather than enucleation in order to obviate recurrence. Here, we report a case of bilateral GOC in the anterior region of the maxilla, in a 29-year-old male patient, which is very unusual as it is the first bilateral case to be reported in the literature.

Keywords


Glandular Odontogenic Cyst, Maxilla, Bilateral.

References





DOI: https://doi.org/10.18311/ijmds%2F2014%2F81305