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Oxidative Stress in Relation to Obesity in Gujrati and Non Gujarati Young Girls before and after Maize Diet


Affiliations
1 Biochemistry, Pacific University, Udaipur,Rajasthan, India
2 Biochemistry, RNT Medical College, Udaipur, Rajasthan, India
3 Pharmacology, GIDSR, Ferozepur, India
4 Oral and Maxillofacial Pathology, Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, India
 

Background: Obesity is the first of the "diseases of civilization" to appear. Its prevalence is escalating at an alarming rate. Environmental and behavioral changes brought about by economic development, modernization and urbanization has been linked to the rise in global obesity. Obesity may induce systemic oxidative stress.

Objective: The present scenario suggests that higher oxidative stress is the key factor of obesity and hence a management strategy aiming at control of lipid peroxidation in obesity by use of maize diet is envisaged.

Material and methods: This study has been conducted on 1001 Gujarati and non Gujarati girls aged between 18-30 years. They were further distributed according to age, inhabitance, socio economic status, dietary habits, family history and blood pressure. Every subject in each group was asked to replace the wheat chapatti by maize chapatti for 30 days; the girls were examined for oxidative stress parameter MDA before and after maize diet along with the statistical evaluation.

Results: There was a positive effect of maize diet on biochemical parameter of all the girls in all the subgroups Malondialdehyde level in total girls before the maize diet was 2.35 ± 0.76nmol/ml which reduced to 1.8 ± 0.46nmol/ml after the diet (P<0.001).

Conclusions: The oxidative stress showed improvement in normal, overweight and obese girls, most significantly on overweight and obese girls after taking the diet (P<0.001). Current dietetic practice is to recommend a healthy eating plan of reduced fat, and increased fiber intake.


Keywords

Obesity, Prevalence, Oxidative Stress, Malondialdehyde (MDA), Dietary Fiber.
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  • Buege JA, Aust SD. The thiobarbituric acid assay. Methods Enzymol 1978;52:306.

  • Reddy KK, Ramamurty R, Papa Rao. Free radical and antioxidant status in urban and rural Tirupati men. Asia Pacific J Clin nutr 1997;6:296-311.

  • Olusi SO. Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotective enzymes in humans. Obesity 2002;26:1159-64.

  • Sharma JP, Rastogi V, Niaz MA. Socioeconomic status and obesity. Eur Heart J 1997;18:588-95.

  • Peiris AN, Thakur RK. Relationship of regional fat distribution and obesity. South Med J 1991;84:961–5.

  • Bjorntorp P. Classification of obese patients and complications related to the distribution of surplus fat. Nutrition 1990;6:131–7.

  • Singh SP, Sikri G, Garg MK. Body mass index and obesity. Tailoring cut off for an Asian Indian male population. MJAFI 2008;64:350-3.

  • Sparks JD, Sparks CE. Lipoprotein synthesis and secretion. Biochimica Biophysica Acta 1994;1215:9-32.

  • Trowell, Tsai AW. Cardiovascular risk factors. Arch Intern Med 1972;162:1182–9.

  • Tungland BC, Meyer D. Nondigestible oligo and polysaccharides, their role in human health. Food Science 2002;173-89.

  • Van Itallie TB. Dietary fiber and obesity. American Journal of Clinical Nutrition 1978;31:S43-52.

  • Zannad F, Gille B, Grentzinger A. Weight reduction. Am Heart J 2002;144:508–15.

  • Arcaro G, Zamboni M, Rossi L, Turcato E, Covi G, Armellini F, Lechi A et al. Body fat distribution. Int J Obes Relat Metab Disord 1999;23:936–42.

  • Ardern CI, Janssen I, Ross R, Katzmarzyk PT. Development of waist circumferences thresholds within BMI categories. Obes Res 2004;12:1094.

  • Barzilai N, Gupta G. Pathophysiology of fat distribution. Ann N Y Acad Sci 1999; 892:58-72.

  • Bray GA. Nutrient balance and obesity. Med Clin North Am 1989;73.

  • Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome. Arch Intern Med 2003;163:427–36.

  • Pradeep Kumar, Vikas K, Kosambia JK. Prevalence of hypertension among the employs of south Gujarat. Indian Journal of Community Medicine 2002;27:19-22.

  • Perry AC, Applegate EB, Allison ML, Miller PC, Signorile JF. Relation between anthropometric measurements of fat distribution in overweight and obese females. Am J Clin Nutr 1997;66:829-36.

  • Pi-Sunyer FX, Aronne LJ, Heshmati HM. Weight measurements. JAMA 2006;295: 761-75.

  • Simin Liu. Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle aged women. Am J Clin Nutr 2003;78:920-7.

  • Slavin J. Dietary fiber and body weight. Nutrition 2009;21:411-18.

  • Voors AW, Webber LS, Frerichs RR, Berenson GS. Body height and body mass. Am J Epidemiol 1997;106:101– 8.

  • Sharma JP, Rastogi V, Niaz M. Socioeconomic status and obesity. Eur Heart J 1997;18:588-95.

  • Durnin JV, Rahaman MM. The assessment of the amount of fat in the human body from measurements of skin fold thickness. Br J Nutr 1967;21:681.

  • Nora E, Straznicky, Christopher J, Vicki E, Wilkliams J. Obesity 2008;34:580.


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  • Oxidative Stress in Relation to Obesity in Gujrati and Non Gujarati Young Girls before and after Maize Diet

Abstract Views: 252  |  PDF Views: 125

Authors

Nita Sahi
Biochemistry, Pacific University, Udaipur,Rajasthan, India
Ashok Kumar Verma
Biochemistry, RNT Medical College, Udaipur, Rajasthan, India
Roopinder Kaur
Pharmacology, GIDSR, Ferozepur, India
Manveen Kaur Jawanda
Oral and Maxillofacial Pathology, Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, India

Abstract


Background: Obesity is the first of the "diseases of civilization" to appear. Its prevalence is escalating at an alarming rate. Environmental and behavioral changes brought about by economic development, modernization and urbanization has been linked to the rise in global obesity. Obesity may induce systemic oxidative stress.

Objective: The present scenario suggests that higher oxidative stress is the key factor of obesity and hence a management strategy aiming at control of lipid peroxidation in obesity by use of maize diet is envisaged.

Material and methods: This study has been conducted on 1001 Gujarati and non Gujarati girls aged between 18-30 years. They were further distributed according to age, inhabitance, socio economic status, dietary habits, family history and blood pressure. Every subject in each group was asked to replace the wheat chapatti by maize chapatti for 30 days; the girls were examined for oxidative stress parameter MDA before and after maize diet along with the statistical evaluation.

Results: There was a positive effect of maize diet on biochemical parameter of all the girls in all the subgroups Malondialdehyde level in total girls before the maize diet was 2.35 ± 0.76nmol/ml which reduced to 1.8 ± 0.46nmol/ml after the diet (P<0.001).

Conclusions: The oxidative stress showed improvement in normal, overweight and obese girls, most significantly on overweight and obese girls after taking the diet (P<0.001). Current dietetic practice is to recommend a healthy eating plan of reduced fat, and increased fiber intake.


Keywords


Obesity, Prevalence, Oxidative Stress, Malondialdehyde (MDA), Dietary Fiber.

References





DOI: https://doi.org/10.18311/ijmds%2F2014%2F80683