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Penicillum marneffi Infection Presenting as Lump Abdomen
Penicillum marneffi is the third leading opportunistic pathogen in HIV endemic areas. We report a case, with a rare clinical presentation as lump abdomen with newly diagnosed HIV-1 antibody reactive status. A diagnosis was made by endoscopic biopsy of growth in second part of duodenum which on histopathology and culture detected Penicillum Marneffi. He was treated with intravenous amphotericin B for 2 weeks followed by oral itraconazole. This case is reported for its unusual presentation to sensitize clinicians to consider this as an etiology in patients in HIV endemic areas who present as lump abdomen.
Keywords
HIV, AIDS, Lump Abdomen, Penicillum marneffei, Opportunistic Pathogen.
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- Wu TC, Chan JW, Ng CK, Tsang DN, Lee MP, Li PC, et al. Clinical presentations and outcomes of Penicillum Marneffi infection: a series from 1994 to 2004. Hong Kong med J 2008; 14(2):103-09. [Pub Med]
- Suppuratpinyo K, Khamwan C, Baosoung V, Nelson KE, Sirisanthana T. Disseminated Penicillum Marneffi infection in southeast Asia. Lancet 1994; 344:110-3. [Pub Med]
- Viviani MA, Vanittanakom N. Topley & Wilson’s Microbiology and Microbial infections- Medical Mycology. 10th edition. London: Hodder Arnold; 2005:560-576.
- Sirisanthana T, Suppuratpinyo K. Epidemiology and management of Penicillosis in human immunodeficiency virus-infected patients. Int J Infect Dis 1998; 3:48-53.
- Vanittanakom N, Cooper CR Jr, Fisher MC, Sirisanthana T. Penicillum Marneffi Infection and recent advances in the epidemiology and molecular biology aspects. Clin Microbiol Rev 2006; 19:95-110.
- Singh PN, Ranjana KH, Singh YI, Singh KP, Sharma SS, Kulachandra M et al. Indigenous Disseminated Penicillum Marneffi Infection in the state of Manipur, India: Report of four Autochthonous Cases. J Clin Microbiol 1999; 37(8):2699–2702.
- Ukarapol N, Sirisanthana V, Wongsawasdi Al. Penicillium Marneffi mesenteric lymphadenitis in human immunodeficiency virus-infected children. J Med Assoc Thai 1998; 81:637-40.
- KO Cl, Hung CC, Chen MY, Hsueh PR, Hsiao CH, Wong JM. Endoscopic diagnosis of intestinal penicillum Marneffi: Report of three cases and review of literature. Gastrointest Endosc 1999; 50:111-14.
- George IA, Sudarsanam TD, Pulimood AB, Mathews MS. Acute abdomen: an unusual presentation of disseminated Penicillum Marneffi infection. Indian J Med Microbiol 2008; 26(2):180-2.
- Suppuratpinyo K, Khamwan C, Baosoung V, Nelson KE, Sirisanthana T. Disseminated Penicillum Marneffi infection in Southeast Asia. Lancet 1994; 344:110-13.
- Antinori S, Gianelli E, Bonaccorso C, Ridolfo AL, Croce F, Sollima S, et al. Disseminated Penicillum Marneffi infection in an HIV-positive Italian patient and a review of cases reported outside endemic regions. J Travel Med 2006; 13(3):181-188.
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