International Journal of Medical and Dental Sciences

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Effectiveness of Kampo Medicines Against Intractable Stomatitis:A Mini-Review


Affiliations
1 Graduate, Department of Oral Medicine, Institute of Biomedical Sciences, Tokushima University Kuramoto 3-18-15, Tokushima 770-8504, Japan
 

Intractable stomatitis is a chronic inflammatory disease of oral mucosa, with unclear etiopathogenesis. Kampo Medicines (KMs), i.e., Japanese herbal medicines, effectively treat stomatitis. The precise effects of KMs on intractable stomatitis are not established. We present the details of several patients with intractable stomatitis who were well-treated with KMs (i.e., Inchinkoto, Orento, Goreisan, and Byakkokaninjinto). We also review the literature on the link between intractable stomatitis and KMs. KM-related anti-inflammatory and antioxidant activity may suppress intractable stomatitis. KMs may also facilitate wound healing through increased saliva secretion. KMs may therefore be useful for the treatment of intractable stomatitis.


Keywords

Anti-Inflammatory Activity, Antioxidant Activity, Intractable Stomatitis, Kampo Medicines, Saliva Secretion.
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  • Effectiveness of Kampo Medicines Against Intractable Stomatitis:A Mini-Review

Abstract Views: 247  |  PDF Views: 103

Authors

Yukihiro Momota
Graduate, Department of Oral Medicine, Institute of Biomedical Sciences, Tokushima University Kuramoto 3-18-15, Tokushima 770-8504, Japan
Hideyuki Takano
Graduate, Department of Oral Medicine, Institute of Biomedical Sciences, Tokushima University Kuramoto 3-18-15, Tokushima 770-8504, Japan
Masayuki Azuma
Graduate, Department of Oral Medicine, Institute of Biomedical Sciences, Tokushima University Kuramoto 3-18-15, Tokushima 770-8504, Japan

Abstract


Intractable stomatitis is a chronic inflammatory disease of oral mucosa, with unclear etiopathogenesis. Kampo Medicines (KMs), i.e., Japanese herbal medicines, effectively treat stomatitis. The precise effects of KMs on intractable stomatitis are not established. We present the details of several patients with intractable stomatitis who were well-treated with KMs (i.e., Inchinkoto, Orento, Goreisan, and Byakkokaninjinto). We also review the literature on the link between intractable stomatitis and KMs. KM-related anti-inflammatory and antioxidant activity may suppress intractable stomatitis. KMs may also facilitate wound healing through increased saliva secretion. KMs may therefore be useful for the treatment of intractable stomatitis.


Keywords


Anti-Inflammatory Activity, Antioxidant Activity, Intractable Stomatitis, Kampo Medicines, Saliva Secretion.

References





DOI: https://doi.org/10.18311/ijmdsjssmes%2F2019%2F184476