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Role of Stress in Newly Detected Type 2 Diabetes Mellitus and Hypertension


Affiliations
1 Department of Internal Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India
2 Dept of physiology, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India
 

Background: Type 2 diabetes mellitus and hypertension are chronic diseases whose prevalence is increasing globally. Cardiovascular disease is a major cause of mortality and morbidity in diabetes and hypertension, and lifestyle and clinical risk factor do not fully account for the link between the conditions.

Objective: This study provides an overview of the evidences concerning the role of stressful life events as contributors of increasing the risk of developing type 2 diabetes mellitus and hypertension in the population.

Material and Methods: Prospective cross-sectional study comprising of 80 random cases of newly detected type 2 diabetes and hypertension. Strength of association with the outcome endurance of diabetes mellitus and hypertension with stress levels grouped as slight risk, moderate risk and at risk was evaluated and reported as RR (relative risk) with corresponding 95% confidence interval (CI) x^2 used for trend, p-value of <0.05 was considered as statistically significant.

Results: Strong association found between exposure to stress and development of type 2 diabetes mellitus (RR=1.51, 95% CI=1.09-2.10) (p=0.02). A positive linear trend was observed between hypertension and stress. For SBP (x^2 for trend=18.5, df=2, p=0.0001 highly significant). DBP 7 times more risk of developing hypertension (RR=7.36, 95% CI=1.27-4.94), p=0.0006 (highly significant).

Conclusion: Strong association was found between stress and development of hypertension and type 2 diabetes mellitus. In hypertensive's a positive linear trend was seen between the two variables. In the diabetics, the relative risk with stress was 1.5 times. Stressful life events increase the risk of developing Type2 diabetes and hypertension.


Keywords

Type 2 Diabetes Mellitus, Stress, Hypertension, Association, Life.
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  • Reddy KS. Regional case studies – India. Nestle Nutr Workshop Ser Pediatr Program 2009; 63 :15-24. discussion 41-46,259-268.
  • Beilin LJ, Puddey IB, Burke V. Lifestyle and hypertension. Am J Hypertens 1992;12:934-45.
  • Weissmann G. The Experimental Pathology of Stress: Hans Selye to Paris Hilton. The FASEB Journal 2007;21:2635-8.
  • Pedrizet GA. Hans Selye and beyond: responses to stress. Cell Stresses and Chaperones 1997;2(4):214-9.
  • Mohan V, Seedat YK, Pradeepa R. The rising burden of diabetes and hypertension in Southeast Asian and African regions: Need for effective strategies for prevention and control in Primary Health Care setting. International Journal of Hypertension 2013; ID 409083.
  • WHO. World Health Day 2016: Diabetes Accessed on 31-01-2017 URL: www.searo.who.Int/india/mediacentre/events/2016/en
  • Anchala R, Kannuri NK, Pant H, Franco OH, Di Angelantonio E, Prabheharan D. Hypertension in India: a systemic review and meta – analysis of prevalence awareness, and control of hypertension J Hypertens 2014;32(6):1170-77.
  • Lucini D, Norbiato G, Clerici M, Pagani M. Hemodynamic and autonomic adjustments to real life stress conditions in humans. Hypertension 2002;39:184-8.
  • Ebigbo PO, Oli JM. Stress in the life of Nigerian diabetics. Z Psychosom Med Psychoanal 985;31(3):267-83.
  • Vrijkotte TGM, van Doornen LJP, de Geus EJC. Effects of work stress on ambulatory blood pressure, heart rate and heart rate variability. Hypertension 2000;35:880-6.
  • Zimmet PZ. Type - 2(non-insulin-dependent) diabetes-an epidemiological overview. Diabetologia 1982;22:399-411.
  • Dutt D, Roy G, Chatterjee P. Risk factor assessment for Type – II diabetes mellitus in a tertiary hospital in Kolkata. Indian Journal of community Medicine 2004;29(4):10-2.
  • Agardh EE, Ahlbom A, Andersson T, Efendic S, Grill V, Hallqvist J, et al. Work stress and low sense of coherence is associated with type - 2 diabetes in middle – aged Swedish women. Diabetes Care 2003;26:719-24.
  • D Foskolos. Stress,depression and Alzheimer’s disease: The triangle of obilion? Encephalos journal 2011;48(3):131-6.
  • Tsigos C, Kyrou I, Chrousos G. Stress, endocrine physiology and pathophysiology. Accessed on 26-05-2017. URL:www.endotext.org/chapter/page/9/

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  • Role of Stress in Newly Detected Type 2 Diabetes Mellitus and Hypertension

Abstract Views: 228  |  PDF Views: 106

Authors

Bavneet Kaur
Department of Internal Medicine, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India
Upneet Bedi
Dept of physiology, Punjab Institute of Medical Sciences, Jalandhar, Punjab, India

Abstract


Background: Type 2 diabetes mellitus and hypertension are chronic diseases whose prevalence is increasing globally. Cardiovascular disease is a major cause of mortality and morbidity in diabetes and hypertension, and lifestyle and clinical risk factor do not fully account for the link between the conditions.

Objective: This study provides an overview of the evidences concerning the role of stressful life events as contributors of increasing the risk of developing type 2 diabetes mellitus and hypertension in the population.

Material and Methods: Prospective cross-sectional study comprising of 80 random cases of newly detected type 2 diabetes and hypertension. Strength of association with the outcome endurance of diabetes mellitus and hypertension with stress levels grouped as slight risk, moderate risk and at risk was evaluated and reported as RR (relative risk) with corresponding 95% confidence interval (CI) x^2 used for trend, p-value of <0.05 was considered as statistically significant.

Results: Strong association found between exposure to stress and development of type 2 diabetes mellitus (RR=1.51, 95% CI=1.09-2.10) (p=0.02). A positive linear trend was observed between hypertension and stress. For SBP (x^2 for trend=18.5, df=2, p=0.0001 highly significant). DBP 7 times more risk of developing hypertension (RR=7.36, 95% CI=1.27-4.94), p=0.0006 (highly significant).

Conclusion: Strong association was found between stress and development of hypertension and type 2 diabetes mellitus. In hypertensive's a positive linear trend was seen between the two variables. In the diabetics, the relative risk with stress was 1.5 times. Stressful life events increase the risk of developing Type2 diabetes and hypertension.


Keywords


Type 2 Diabetes Mellitus, Stress, Hypertension, Association, Life.

References





DOI: https://doi.org/10.18311/ijmds%2F2017%2F149904