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To explain the effectiveness of different oral and intravenous (IV) Proton Pump Inhibitors (PPI) used in the management of peptic ulcer re-bleeding after successful endoscopic intervention. This article offers the summarization of various articles on PPI which are published in a well-known journals. All the articles used the same method in the management of peptic ulcer re-bleeding. Rockall risk scoring system were used for grading the rate of the bleeding. Pubmed and Embase was used to identify the related articles that assessed the efficacy of PPI and found Six articles matched our criteria. All the results where P<0.05 where considered significant for writing this review article. Neither any alterations or modifications nor any softwares were used in this article. All the results and conclusions were briefed and summarized carefully after a through discussion of the articles included in our review.

Keywords

Proton Pump Inhibitors (PPI), Endoscopic Therapy, Rebleeding, Peptic Ulcer, Hemostasis, Mortality Rate, Surgical Rate.
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